Biodistribution of dry kit macroaggregat albumin (MAA) 99m-Tc

Macroaggregat albumin has been successfully labelled with technetium-99m to fulfill lungs visualization purposes. Human lung may be scanned immediately after intravenous injection of 20-90 um size of radioalbumin aggregates because they are temporarily trapped in the lung capillaries. Biodistribution studies in rats have demonstrated the feasibility, and wide margin of safety for performing human scans with this test material. Clinical trial were initiated in patients with normal and abnormal lungs. Results indicated the lung scan itself has diagnostic value. (athors). 7 refs.; 2 tabs.; 4 figs