Published 1990
| Version v1
Book
Non-stoichiometric fluorochrome binding induced by X-rays in G0/G1 lymphocytes shown by BRDU/Hoechst flow cytometry
Description
Clastogenic agents like X-rays induce different types of DNA-damage, primarily single and/or double strand breaks. Alterations of chromatin structure might be recognized by changes of the DNA-fluorochrome binding capacity of the total population. In this report the induction of a distinct non-cycling G0/G1-cluster with lower Hoechst fluorescence intensity in human PBL is shown after treatment with X-rays, and inhibition of DNA-ligase by 4-hydroxybenzamide. (author). 5 refs.; 1 fig.; 1 tab
Additional details
Publishing Information
- Publisher
- Excerpta Medica.
- Imprint Place
- Amsterdam (Netherlands)
- ISBN
- 0 444 81358 6
- Imprint Title
- Advances in analytical cellular pathology
- Imprint Pagination
- 344 p.
- Journal Issue
- no. 911
- Series
- International Congress Series.
- Journal Page Range
- p. 289-290.
Conference
- Title
- 1. Conference of the European Society for Analytical Cellular Pathology.
- Dates
- 12-17 Nov 1989.
- Place
- Schloss Elmau (Germany, F.R.).
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 22050648
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CYTOLOGICAL TECHNIQUES; DNA; DYES; LYMPHOCYTES; STRAND BREAKS; X RADIATION
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; LEUKOCYTES; MATERIALS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATIONS; SOMATIC CELLS
Optional Information
- Notes
- Imprint:Includes index of authors and subject index.