Published February 1976 | Version v1
Journal article Metadata-only

A preliminary experiment on regression of human ovarian tumor transplants in athymic nude mice following a single exposure to 60Co radiation

Creators

  • 1. Norske Radiumhospital, Oslo
  • 2. Norsk Hydro, Oslo

Description

Human ovarian tumor transplants (AN-LE) are grown in the thymus defective nude mouse mutant (nu/nu BALB/c/A/Bom). Procedures for local irradiation of the tumors with 60Co-radiation are described. An introductory test of the usefulness of these transplants in studies of radiation effects on human tumors is performed by investigation of the time course of regression of AN-LE transplants in 6 mice, following single exposures to 375, 750, 1180 and 1575 rad, respectively. (author)

Additional details

Identifiers

DOI
10.3109/02841867609132707;

Publishing Information

Journal Title
Acta Radiologica: Therapy, Physics, Biology
Journal Volume
15
Journal Issue
1
Series
Acta Radiol., Ther., Phys., Biol.
Journal Page Range
43-48
ISSN
0567-8064

INIS

Country of Publication
Sweden
Country of Input or Organization
Sweden
INIS RN
7251352
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
COBALT 60; DELAYED RADIATION EFFECTS; GRAFTS; IN VIVO; LOCAL IRRADIATION; LOCAL RADIATION EFFECTS; MICE; NEOPLASMS; RADIOSENSITIVITY; TEMPORAL DOSE DISTRIBUTIONS; TIME DEPENDENCE; TUMOR CELLS
Descriptors DEC
ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; COBALT ISOTOPES; DISEASES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; RADIATION DOSE DISTRIBUTIONS; RADIATION EFFECTS; RADIOISOTOPES; RODENTS; TRANSPLANTS; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
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