Third recurrence of cardiac myxoma in a Carney complex patient

Primary cardiac tumors are an uncommon entity with an incidence of 0.3-0.7%. Most primary cardiac neoplasms are benign, with cardiac myxoma (CM) being the most prevalent type. Patients with CM may present symptoms due to embolic phenomena or intracardiac blood flow obstruction for which the treatment is surgical resection. Postoperative tumor recurrence occurs in up to 3% of cases; however, when myxomas are part of an underlying genetic syndrome, the recurrence rate can reach 22%. The main syndrome associated with this recurrence is the Carney complex (CNC). First described in 1985 by J. Aidan Carney, CNC is defined as an extremely rare autosomal dominant genetic syndrome with main clinical characteristics including skin pigmentation, heart myxomas, and endocrine neoplasms. (author)