Published 1990 | Version v1
Journal article Metadata-only

The effect of Adeturon on mouse oocyte survival to gamma irradiation

Creators

  • 1. Meditsinska Akademiya, Sofia (Bulgaria). Nauchen Inst. po Rentgenologiya i Radiobiologiya

Description

The protective effect of Adeturon (S-2-aminoehylisothiuronic adenosine-5-triphosphate) in dose of 300 mg/kg b.w. at acute gamma irradiation (12,9 mC/kg) is studied using mouse oocyte survival as a test system. A significant toxicity of the agent was observed changing in different follicle stages. It was found not only a full absent of radioprotective effect on the oocytes, but an increase in the radiation damage as well. 1 tab., 21 refs

Additional details

Publishing Information

Journal Title
Problemi na Nuklearnata Meditsina, Radiobiologiyata i Radiatsionnata Khigiena
Journal Volume
11
Series
Probl. Nukl. Med., Radiobiol. Radiat. Khigiena.
Journal Page Range
49-52
CODEN
PNMKE

INIS

Country of Publication
Bulgaria
Country of Input or Organization
Bulgaria
INIS RN
23014389
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
ACUTE IRRADIATION; AET; ATP; BIOLOGICAL RADIATION EFFECTS; CELL KILLING; EXPERIMENTAL DATA; GAMMA RADIATION; MICE; OOCYTES; RADIATION PROTECTION; RADIOPROTECTIVE SUBSTANCES; SURVIVAL CURVES; TOXICITY
Descriptors DEC
ACUTE EXPOSURE; AMINES; ANIMALS; BIOLOGICAL EFFECTS; CARBONIC ACID DERIVATIVES; DATA; DRUGS; ELECTROMAGNETIC RADIATION; GERM CELLS; INFORMATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; NUCLEOTIDES; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; RADIATION EFFECTS; RADIATIONS; RESPONSE MODIFYING FACTORS; RODENTS; THIOUREAS; VERTEBRATES