Published September 2013
| Version v1
Journal article
A case of laryngeal necrosis following concurrent chemoradiotherapy for advanced hypopharyngeal cancer after insertion of a nasogastric tube
Creators
- 1. Osaka Univ., Graduate School of Medicine, Suita, Osaka (Japan)
- 2. Sakai Municipal Hospital, Sakai, Osaka (Japan)
Description
A 62-year-old male with cT4bN2cM0 hypopharyngeal carcinoma with ipsilateral vocal cord fixation was initially treated with concurrent chemoradiotherapy. Since the patient complained of dysphagia caused by mucositis, a nasogastric tube was placed on the day of irradiation with a dose of 20 Gy. Bilateral vocal cord fixation and laryngeal necrosis became evident 3 weeks after the concurrent chemoradiotherapy. He underwent a total pharyngolaryngectomy (neck dissection, and reconstruction with a free jejunal graft) followed by adjuvant chemotherapy. It is highly suspected that the nasogastric tube compressed the mucosa of the post cricoid region, resulting in laryngeal necrosis. (author)
Additional details
Publishing Information
- Journal Title
- Nippon Jibi Inkoka Gakkai Kaiho
- Journal Volume
- 116
- Journal Issue
- 9
- Journal Page Range
- p. 1041-1045
- ISSN
- 0030-6622
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 45035903
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ABSORBED RADIATION DOSES; CARCINOMAS; CHEMOTHERAPY; COMBINED THERAPY; EARLY RADIATION EFFECTS; FRACTIONATED IRRADIATION; GY RANGE 01-10; GY RANGE 10-100; LARYNGECTOMY; LARYNX; NECROSIS; PATIENTS; PHARYNX; RADIOTHERAPY
- Descriptors DEC
- ABSORBED DOSE RANGE; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DIGESTIVE SYSTEM; DISEASES; DOSES; GY RANGE; IRRADIATION; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; PATHOLOGICAL CHANGES; RADIATION DOSE RANGES; RADIATION DOSES; RADIATION EFFECTS; RADIOLOGY; RESPIRATORY SYSTEM; SURGERY; THERAPY