Published October 2012 | Version v1
Journal article Metadata-only

Biosynthesis of two dihydropyrrole-polyketides from a marine-derived Penicillium citrinum

Creators

  • 1. Universidade de Sao Paulo (USP), Sao Carlos, SP (Brazil). Inst. de Quimica
  • 2. Universidade Federal de Sao Carlos (UFSCAR), SP (Brazil). Dept. de Quimica

Description

Feeding experiments with 13C-labeled precursors were performed in order to establish the biosynthesis of two N-acylated dihydro pyrroles, (8E)-1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldec- 8-ene-1,3-dione (1) and 1-(2,3-dihydro-1H-pyrrol-1-yl)-2-methyldecane-1,3-dione (2), isolated from the cultures of a marine-derived Penicillium citrinum. The biosynthesis of both, 1 and 2, involves the incorporation of acetate, methionine and ornithine. (author)

Availability note (English)

Available from http://www.scielo.br/pdf/jbchs/v23n10/aop078_12.pdf

Additional details

Identifiers

URL
http://www.scielo.br/pdf/jbchs/v23n10/aop078_12.pdf;

Publishing Information

Journal Title
Journal of the Brazilian Chemical Society
Journal Volume
23
Journal Issue
10
Journal Page Range
p. 1783-1788
ISSN
0103-5053
CODEN
JOCSET

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
44080245
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
ACETATES; CARBON 13; LABELLED COMPOUNDS; LIQUID COLUMN CHROMATOGRAPHY; MASS SPECTRA; METHIONINE; NMR SPECTRA; ORNITHINE; PENICILLIUM; PRECURSOR; PYRROLES; SODIUM; TOXICITY; ULTRAVIOLET SPECTRA
Descriptors DEC
ALKALI METALS; AMINO ACIDS; AZOLES; CARBON ISOTOPES; CARBOXYLIC ACID SALTS; CARBOXYLIC ACIDS; CHROMATOGRAPHY; DRUGS; ELEMENTS; EUMYCOTA; EVEN-ODD NUCLEI; FUNGI; HETEROCYCLIC COMPOUNDS; ISOTOPES; LIGHT NUCLEI; LIPOTROPIC FACTORS; METALS; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC SULFUR COMPOUNDS; PLANTS; SEPARATION PROCESSES; SPECTRA; STABLE ISOTOPES