Published 1977 | Version v1
Miscellaneous Restricted

Protein A-containing staphylococcus aureus as an immunoglobulin-binding reagent: 1) in radioimmunoassays - 'staf-RIA' - recently also for antibiotics and microbial antigens/antibodies, and 2) in a non-radioactive surface immunoassay - 'Staph-ace ay' read by the naked eye - primarily for antibodies to antigens adsorbed to transparent surfaces

Creators

  • 1. Kaernsjukhuset, Skoevde (Sweden). Dept. of Clinical Bacteriology

Description

This paper is intended to summarize recent developments for the use of protein A-containing staphylococci as an immunoglobulin-binding reagent in various types of radioimmunoassay and some related areas, particularly the staphylococcal surface immunoassay. The paper also presents a new process for the large scale preparation of a freeze-dried preparation of the immunoglobulin-binding, killed staphylococci, which thereby gain a much improved suspension stability. (orig.)

Availability note (English)

MF available from INIS under the Report Number.

Abstract (German)

Diese Arbeit versucht, neueste Entwicklungen auf dem Gebiet der Anwendung von Protein A-haltigen Staphylokokken als immunoglobalin-bindende Reagenzen in verschiedenen Arten von Radioimmunoassays und einigen verwandten Gebieten aufzuzeigen, vor allem den staphylokokkischen Oberflaechen-Immunoassay. Die Arbeit stellt auch einen neuen Prozess fuer die gefriergetrocknete Vorbereitung von immunoglobulin-bindenden, abgetoeteten Staphylokokken vor, die dadurch eine viel bessere Suspensionsstabilitaet gewinnen. (orig.)

Files

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Additional details

Publishing Information

Imprint Pagination
13 p.
Report number
AED-Conf--77-461-031

Conference

Title
International symposium on radioimmunoassay and related procedures in medicine.
Dates
31 Oct - 4 Nov 1977.
Place
Berlin, Germany, F.R.

Optional Information

Notes
3 figs.; 2 tabs.; 43 refs.
Secondary number(s)
IAEA-SM--220/53.