Effectiveness of lead apron towards effective dose on Lu¹⁷⁷ therapy

Radio labeled PSMA-617 (prostate specific membrane antigen) is potential therapeutic target in the treatment of prostate cancer and radiolabeled DOTA-TATE for neuroendocrine tumor (NET). The purpose of the study was to assess the effectiveness of lead apron while administration of 177 Lutetium (¹⁷⁷ Lu) radiopharmaceuticals. 200mCi of Lutetium-177 PSMA was administered to the patient. While administrating the dose two pocket dosimeter were used to find effectiveness of lead apron. One dosimeter was placed inside the lead apron and another one was placed outside to monitor the effective dose to radiation professional . Both the dosimeter were placed at the chest level. The pocket dosimeter kept outside the lead apron showed 8μSv while that kept inside 2μSv while administering 200mCi of ¹⁷⁷Lu PSMA-617. The study concluded that lead apron reduces the effective dose to 1/4th . Hence it proves that using lead apron reduces the effective dose to radiation professional at the time of administration Lu177 therapy