Published November 1999 | Version v1
Journal article Metadata-only

The preparation of 188Re labelled stannic sulfur suspension and preliminary animal experiment

Creators

  • 1. Academia Sinica, SH (China). Shanghai Inst. of Nucledar Research
  • 2. Shanghai Railway Hospital, Shanghai (China)

Description

188Re labelled stannic sulfur suspension was prepared with two-steps: At first acid 188Re labelled suspension was obtained by adding stannous chloride into acidic solution of 188Re perrhenate and sodium thiosulphate, then adjust the pH of the solution to neutral point with NaOH and Na2HPO4 and 188Re labelled stannic sulfur suspension was formed. The particles sizes of this suspension were 2-5 μm mainly. The radiochemical purity was above 95%. The suspension was stable in vitro and vivo tests. Finally, animal experiments observed that the tumor inhibiting rate of this 188Re labelled stannic sulfur suspension was 90% in human glioma bearing nude mice

Additional details

Publishing Information

Journal Title
Nuclear Techniques
Journal Volume
22
Journal Issue
11
Journal Page Range
p. 690-694
ISSN
0253-3219

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
31009859
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CHEMICAL PREPARATION; IMPURITIES; LABELLED COMPOUNDS; LABELLING; NEOPLASMS; RHENIUM 188; STABILITY; SULFUR; SUSPENSIONS; TIN
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DISEASES; DISPERSIONS; ELEMENTS; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; METALS; MINUTES LIVING RADIOISOTOPES; NONMETALS; NUCLEI; ODD-ODD NUCLEI; RADIOISOTOPES; RHENIUM ISOTOPES; SYNTHESIS