Long term outcomes of new generation drug eluting stents versus coronary artery bypass grafting for multivessel and/or left main coronary artery disease. A Bayesian network meta-analysis of randomized controlled trials

Highlights: • CABG is associated with lower MACE when compared to old generation stents but not when compared to new generation DES. • There is no significant difference between CABG and PCI in mortality, CVA and MI. • CABG is associated with lower repeat revascularization when compared to PCI. - Abstract: BackgroundMost data guiding revascularization of multivessel disease (MVD) and/or left main disease (LMD) favor coronary artery bypass grafting (CABG) over percutaneous coronary intervention (PCI). However, those data are based on trials comparing CABG to bare metal stents (BMS) or old generation drug eluting stents (OG-DES). Hence, it is essential to outcomes of CABG to those of new generation drug eluting stents (NG-DES).