Published May 1976
| Version v1
Journal article
Precursor cells of fibroblasts detected by in vitro cloning of cells from hematopoietic organs of normal and irradiated mice
- 1. Akademiya Meditsinskikh Nauk SSSR, Moscow. Inst. Ehpidemiologii i Mikrobiologii
Description
Colonies of fibroblasts are formed in monolayer cultures of bone marrow, spleen, and thymus cells of adult mice with an efficiency of colony formation (per 105 cells) of 2.2 for bone marrow, 0.20 for spleen, and 0.16 for thymus. On irradiation of mice with a dose of 150 r, about half of the fibroblast colony-forming units in the bone marrow die; during the next 6 days their number falls a further fivefold, with a return to the normal level 25 days after irradiation
Additional details
Additional titles
- Original title (Russian)
- Клетки - предшественники фибробластов, выявленные методом клонирования ин витро клеток кроветворных органов нормал'ных и облученных мышей
Identifiers
- DOI
- 10.1007/bf00797159;
Publishing Information
- Journal Title
- Bulletin of Experimental Biology and Medicine
- Journal Volume
- 81
- Journal Issue
- 5
- Series
- Byull. Ehksp. Biol. Med.
- Journal Page Range
- 765-768
- ISSN
- 0007-4888
INIS
- Country of Publication
- USSR
- Country of Input or Organization
- USSR
- INIS RN
- 8310258
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BONE MARROW CELLS; CELL CULTURES; CFU; FIBROBLASTS; IN VITRO; MICE; POPULATIONS; PRECURSOR; SPLEEN CELLS; THYMUS CELLS
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; CONNECTIVE TISSUE CELLS; MAMMALS; RADIATION EFFECTS; RODENTS; SOMATIC CELLS; VERTEBRATES
Optional Information
- Notes
- For English translation see the journal Bull. Exp. Biol. Med.; Updated automatically by Metadata and Full-Text Enrichment Agent