Role of MR enterography in acute and chronic stages of Crohn's disease?,

Crohn's disease (CD) is an autoimmune disease affecting young, adult with relapsing course. MRI is now considered a safe alternative for, diagnosing complication of Crohn's disease. Purpose: To evaluate the value of the MR enterography in acute and chronic stages, of Crohn's disease and compared it to endoscopy. Patients and Methods: Fifty patients of known Crohn's disease aged between 15 and 41 years old, were retrospectively included in this study. Our inclusion criteria were, the following: (1) Crohn's disease proven by tissue diagnosis from the, terminal ileum, (2) complete colonoscopy including examination of the, terminal ileum, (3) no surgical procedure related to Crohn's disease, and, (4) MRE examination done within 20 days from endoscopy. Results: This retrospective study was done on 50 patients; using a 1.5 T MRI. Images were reviewed by two consultant radiologists. We used the endoscopic results of involved small bowel loops as a gold standard reference. MRE as compared to endoscopic finding revealed 97.1% sensitivity, 81.3%, specificity, 91.7% positive predictive value, 92.9% negative predictive, value and 92% accuracy. Conclusion: MR enterography has high significant sensitivity and specificity in, imaging of Crohn's disease as compared to endoscop