Published January 1982
| Version v1
Journal article
Disposition of nickel-63 in the rat
Description
The urinary and faecal excretion of nickel-63(63Ni) and the distribution of 63Ni in kidneys, liver, heart and blood serum after an i.p. injection of radiolabelled nickel chloride (63NiCl2) have been investigated. Most of 63Ni was excreted via urine within 24 h. The daily faecal excretion, though very low, was consistent up to 6 days. The uptake of 63Ni was highest in kidneys and the order was kidneys>serum>heart>liver, 24 h after 63NiCl2 injection. However, 63Ni was eliminated rapidly from the body and there was almost no radioactivity 6 days post administration. (Auth.)
Additional details
Publishing Information
- Journal Title
- Toxicol. Lett.
- Journal Volume
- 10
- Journal Issue
- 1
- Series
- Toxicol. Lett.
- Journal Page Range
- 71-73
- ISSN
- 0378-4274
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 13671464
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BLOOD SERUM; HEART; KIDNEYS; LIVER; NICKEL CHLORIDES; NICKEL 63; RADIONUCLIDE KINETICS; RATS; RETENTION FUNCTIONS; SPATIAL DISTRIBUTION; UPTAKE
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; CHLORIDES; CHLORINE COMPOUNDS; DIGESTIVE SYSTEM; DISTRIBUTION; EVEN-ODD NUCLEI; GLANDS; HALIDES; HALOGEN COMPOUNDS; INTERMEDIATE MASS NUCLEI; ISOTOPES; KINETICS; MAMMALS; NICKEL COMPOUNDS; NICKEL ISOTOPES; NUCLEI; ORGANS; RADIOISOTOPES; RODENTS; TRANSITION ELEMENT COMPOUNDS; VERTEBRATES; YEARS LIVING RADIOISOTOPES