Published May 2005 | Version v1
Journal article

Efficient treatment of pigmented B16 melanoma using photosensitized long-circulating magnetofullerenosomes

  • 1. Department of Biophysics and Chemical Physics, Comenius University, Mlynska dolina F1, 842 48 Bratislava (Slovakia)
  • 2. Department of Radiation Oncology, 987521 Nebraska Medical Center, Omaha, NE 68198 (United States)
  • 3. Department of Civil Engineering, FAMU-FSU College of Engineering, Tallahassee, FL 32310 (United States)

Description

Magnetic targeting was used for melanoma treatment with magnetofullerenosomes. After their intravenous administration, a permanent magnet was attached to the surface of B16 tumors in C57 mice for 24 h, followed by irradiation with an infrared laser pulse and subsequent illumination with a 776 nm diode laser for conventional photodynamic treatment. Tumor response was substantially better than that obtained with either treatment alone

Additional details

Identifiers

DOI
10.1016/j.jmmm.2005.02.042;
PII
S0304-8853(05)00188-5;

Publishing Information

Journal Title
Journal of Magnetism and Magnetic Materials
Journal Volume
293
Journal Issue
1
Journal Page Range
p. 394-397
ISSN
0304-8853
CODEN
JMMMDC

Conference

Title
5. International conference on scientific and clinical applications of magnetic carriers
Dates
20-22 May 2004
Place
Lyon (France)

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
37029325
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ILLUMINANCE; IRRADIATION; LASERS; MELANOMAS; MICE; PERMANENT MAGNETS; THERAPY
Descriptors DEC
ANIMALS; CARCINOMAS; DISEASES; EPITHELIOMAS; EQUIPMENT; MAGNETS; MAMMALS; MEDICINE; NEOPLASMS; RODENTS; VERTEBRATES

Optional Information

Copyright
Copyright (c) 2005 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.