2-beam UV-LED absorption spectroscopy: cold atmospheric plasma diagnostics

Cold atmospheric plasmas (CAPs) are at the focus of the attention due to onward applications such as plasma medicine. The potential of CAP in diverse bio-medical applications has been explored, including disinfection, wound treatments, control of inflammation, blood coagulation, cancer therapy, and regenerative medicine. Since CAP, is delivered essential radicals at room temperature, which results in less damaging effects on living tissue. Intensive studies proved that it is able to inactivate gram-negative and gram-positive bacteria, fungi, virus, spore, various parasites, and foreign organisms or pathogens without harming normal tissue. By using a fine optical emission spectroscopy (OES), the Stark broadening of the Hα-line shall be applied to determine the electron density in the active region of CAP. The gas temperature and vibrational temperature in the afterglow plasma may estimate based on the fitting spectra of N2 second positive system (C3∏u - B3∏g) and Boltzmann plot method, respectively. Thus, the UV-LED absorption spectroscopy could be applied on accumulation of absolute number of RONS radicals to routinely validate the system as medical device. (author)