Multiple tumors. Analysis of 50 patients

The description of multiple primary neoplasms dating from the late nineteenth; Warrem and Gates established the clinicopathological criteria for diagnosis. frequency Clinical presentation is from 1.5 to 5.4% of cancers, and of 5% to 11% by autopsies. In recent years there has been an increase in second tumors probably due to new strategies of staging, monitoring patients (ptes) and therapeutic results with improved survival from first diagnosis. Objective: Analysis of 50 tumor ptes multiple carriers assisted in the HCFF.AA Oncology Service in the period 1/1997 to 1/2004. Patients and methods: ptes included. registered in the H.C.FF.AA, carriers 2 or histologically documented malignant tumors. Were reviewed medical records, describing age, sex, date of diagnosis and type of tumor. Frequency of these tumors and their occurrence interval were analyzed. Results: We included 50 ptes, with 2.0% of registered patients. (2400). The average age was 61 years (36-89 years). Median appearance interval between the first and second tumor was 28 months (0-300). The most common tumors were: breast carcinoma (23), no skin tumors melanoma (15), colon adenocarcinoma (12), prostate (8) and kidney (6). according to appearance 10 were synchronous and 40 metachronous. Breast tumor They most often associated endometrial tumors (5), ovarian (3), colon (3) and kidney (3). Of the 50 patients, 42 had 2 tumors in 8 cases and 3 tumors. Conclusions: The frequency of occurrence of multiple neoplasms in our series and presentation mode in time does not differ from that reported by other authors. Monitoring of patients with cancer and advances in diagnosis Therapeutic and lead to increased tumor diagnosis seconds and a new therapeutic challenge.