Investigation and analysis of eight indicators about hepatitis B in 360 pairs of mother and baby

To explore the infectivity of predelivery women with different modes of hepatitis B virus infections to their fetuses, eight indicators (HBsAg, anti-HBs, HBcAg, anti-HBc, HBeAg, anti-HBe, PHSA-R and anti-HBc-IgM) in serum of mother and umbilical cord blood of baby were detected. By matched pairs the result s showed that there were 170 mothers whose serum was positive for more than one indicator. The positive rate was 47.2% altogether. 15 infections modes appeared. There were 18 mothers whose serum was positive for HBsAg. Of their baby, there were 16 whose umbilical card blood was positive for HBsAg. From mother to baby, the infection rate was 88.8%(16/18). There were two babies whose umbilical cord blood was positive for HBsAg, but the serum of their mother was only positive for anti-HBc. There was one case, the umbilical cord blood of baby was positive for HBsAg, but the serum of his mother was all negative for these eight indicators. (author)