Accelerator-based neutron source for boron neutron capture therapy (BNCT) and method
Description
A source for boron neutron capture therapy (BNCT) comprises a body of photoneutron emitter that includes heavy water and is closely surrounded in heat-imparting relationship by target material; one or more electron linear accelerators for supplying electron radiation having energy of substantially 2 to 10 MeV and for impinging such radiation on the target material, whereby photoneutrons are produced and heat is absorbed from the target material by the body of photoneutron emitter. The heavy water is circulated through a cooling arrangement to remove heat. A tank, desirably cylindrical or spherical, contains the heavy water, and a desired number of the electron accelerators circumferentially surround the tank and the target material as preferably made up of thin plates of metallic tungsten. Neutrons generated within the tank are passed through a surrounding region containing neutron filtering and moderating materials and through neutron delimiting structure to produce a beam or beams of epithermal neutrons normally having a minimum flux intensity level of 1.0x109 neutrons per square centimeter per second. Such beam or beams of epithermal neutrons are passed through gamma ray attenuating material to provide the required epithermal neutrons for BNCT use. 3 figs
Availability note (English)
Available from Patent and Trademark Office, Box 9, Washington, DC 20232 (United States)Additional details
Publishing Information
- Imprint Pagination
- [10 p.]
- IPC:
- Int. Cl. G21H 5/0/0
- IPC
- Int. Cl. G21H 5/0/0
- Patent number
- US patent document 5,903,622/A/
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 30047153
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES; S43: PARTICLE ACCELERATORS; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Non-conventional Literature
- Descriptors DEI
- COOLING SYSTEMS; DESIGN; EPITHERMAL NEUTRONS; LINEAR ACCELERATORS; NEUTRON CAPTURE THERAPY; NEUTRON SOURCES
- Descriptors DEC
- ACCELERATORS; BARYONS; ELEMENTARY PARTICLES; ENERGY SYSTEMS; FERMIONS; HADRONS; MEDICINE; NEUTRON THERAPY; NEUTRONS; NUCLEONS; PARTICLE SOURCES; RADIATION SOURCES; RADIOTHERAPY; THERAPY
Optional Information
- Funding organization
- USDOE, Washington, DC (United States)
- Secondary number(s)
- US patent application 8-713,317