Published 1977
| Version v1
Book
Evaluation by mass fragmentography of metabolic pathways of endogenous and exogenous compounds in eukaryote cell cultures
Description
Carbon-14 labelled compounds in cell cultures are used to establish the interconnections between different metabolic pathways as well as the competitive action of effectors on these different pathways. Analysis was performed by the GC-MS combination. Identification was carried out by comparison with the mass spectra of d9-TMS, 35Cl-TMS and 37Cl-TMS derivatizations of the culture extracts. Examples are given of the metabolic study of hormonal steroids and of safrale, a carcinogenic compound, by differentiated eukaryotic cells in cultures from the rat
Additional details
Additional titles
- Augmented title (English)
- biological pathways
Publishing Information
- Publisher
- Elsevier.
- Imprint Place
- Amsterdam, Netherlands
- ISBN
- 0-444-41557-2
- Imprint Title
- Quantitative mass spectrometry in life sciences
- Imprint Pagination
- p. 49-82.
Conference
- Title
- 1. International symposium on quantitative mass spectrometry in life sciences.
- Dates
- 16 - 18 Jun 1976.
- Place
- Ghent, Belgium.
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 8330489
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CARBON 14 COMPOUNDS; CARCINOGENS; CELL CULTURES; CHLORINE 35; CHLORINE 37; DEUTERIUM COMPOUNDS; DOUBLE LABELLING; GAS CHROMATOGRAPHY; LABELLED COMPOUNDS; MASS SPECTROSCOPY; METABOLISM; RATS; STEROID HORMONES
- Descriptors DEC
- ANIMALS; CARBON COMPOUNDS; CHLORINE ISOTOPES; CHROMATOGRAPHY; HORMONES; HYDROGEN COMPOUNDS; ISOTOPES; LABELLING; LIGHT NUCLEI; MAMMALS; NUCLEI; ODD-EVEN NUCLEI; RADIOACTIVE MATERIALS; RODENTS; SEPARATION PROCESSES; SPECTROSCOPY; STABLE ISOTOPES; VERTEBRATES
Optional Information
- Notes
- 89 refs.