Age-dependent variation of selenium-75 biokinetics in rat
- 1. C.E.A., DSV/DPTE, 91 - Bruyeres le Chatel (France). Lab. de Radiotoxicologie
Description
Substantial levels of 79Se in radioactive waste from the nuclear fuel cycle, may result in a significant collective dose commitment following release into the environment. Whole body retention and organ content were studied in neonate, adult and pregnant rat following oral contamination with 75Se. The results for whole-body retention conformed to a two-component exponential with terminal biological half-time of about 40, 30 and 20 days in adult male, neonate and pregnant rat, respectively. The highest concentrations of Se occurred in the liver, kidney, and testis. Influence of Se kinetics as a function of age and physiological development on dose estimates are discussed. Results were consistent with current dosimetric models but suggested that the testis should also be included. (author)
Additional details
Publishing Information
- Journal Title
- International Journal of Radiation Biology
- Journal Volume
- 64
- Journal Issue
- 3
- Journal Page Range
- p. 329-333.
- ISSN
- 0955-3002
- CODEN
- IJRBE7
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 25002680
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AGE DEPENDENCE; DOSE EQUIVALENTS; DOSE LIMITS; GAMMA RADIATION; ORGANS; POPULATIONS; RADIATION DOSES; RADIOACTIVE WASTES; RADIONUCLIDE KINETICS; RATS; RETENTION; RISK ASSESSMENT; SELENIUM; SELENIUM 75; SELENIUM 79
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; ELECTROMAGNETIC RADIATION; ELECTRON CAPTURE RADIOISOTOPES; ELEMENTS; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KINETICS; MAMMALS; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; RADIATIONS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SAFETY STANDARDS; SELENIUM ISOTOPES; SEMIMETALS; STANDARDS; VERTEBRATES; WASTES; YEARS LIVING RADIOISOTOPES