Assessment of biochemical recurrence of prostate cancer with C-11 choline

To evaluate the diagnostic performance of ¹¹C-choline positron emission tomography-computed tomography (PET/CT) in restaging of biochemical recurrent prostate cancer (PC). In the current study, we were able to identify local and regional recurrence in patients and correctly restage the systemic spread % patient. Hence, choline is also helpful in assessing the effectiveness of anti-androgen therapy or in identification of those who shall need the same. 1C-choline PET/CT is a robust imaging modality for restaging biochemical recurrent PC. It stratifies patients on the basis of local and systemic burden of disease. Thus, the further management in term of local radiotherapy, surgeries or systemic therapies may by be planned. Not only it provides good diagnostic value for detecting local recurrence, but it also helps in radiotherapy planning, either for dose escalation or exclusion of selected sites