Published February 1981 | Version v1
Journal article Metadata-only

Technetium-99m calcium phytate - optimization of calcium content for liver and spleen scintigraphy: concise communication

Creators

  • 1. Inst. of Medical and Veterinary Science, Adelaide, South Australia

Description

The addition of ionic calcium to technetium-99m stannous phytate produced an agent with improved splenic uptake. In a series of patients, it was found that molar ratios of 2:1 and 3:1 produced scans of optimal diagnostic quality. Studies in mice showed dose-related changes in the biodistribution. Electron microscopy demonstrated that the addition of calcium produced progressive aggregation of the colloid as the molar ratio was increased. Chemical analysis of sodium phytate was essential to obtain accurate ratios

Additional details

Publishing Information

Journal Title
J. Nucl. Med.
Journal Volume
22
Journal Issue
2
Series
J. Nucl. Med.
Journal Page Range
157-160
ISSN
0022-3123

Conference

Title
28. annual meeting of Society of Nuclear Medicine.
Dates
16 Jun 1981.
Place
Las Vegas, NV, USA.

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
12616226
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BIOCHEMICAL REACTION KINETICS; BIOLOGICAL LOCALIZATION; CALCIUM; DISTRIBUTION; LIVER; METABOLISM; MICE; PATIENTS; PERFORMANCE TESTING; PHYTIC ACID; RADIOCOLLOIDS; RADIONUCLIDE KINETICS; RESPONSE MODIFYING FACTORS; SCINTISCANNING; SPLEEN; TECHNETIUM 99; TISSUES; UPTAKE
Descriptors DEC
ALKALINE EARTH METALS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COLLOIDS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISPERSIONS; ELEMENTS; ESTERS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KINETICS; LIPOTROPIC FACTORS; MAMMALS; METALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; ORGANS; PHOSPHORIC ACID ESTERS; RADIOISOTOPE SCANNING; RADIOISOTOPES; REACTION KINETICS; RODENTS; TECHNETIUM ISOTOPES; TESTING; VERTEBRATES; YEARS LIVING RADIOISOTOPES