Proton MR spectroscopy in neuroborreliosis: a preliminary study
- 1. Department of Radiology, Medical Academy, Bialystok (Poland)
- 2. Department of Infectious Diseases and Neuroinfections, Medical Academy, Bialystok (Poland)
Description
We report results of a magnetic resonance spectroscopy (MRS) study in 12 patients with neuroborreliosis. We used a PRESS sequence, placing an 8 cm3 voxel in normal-appearing white matter of the frontal lobe. Peaks indicating N-acetylaspartate (NAA), choline (Cho), creatine (Cr), myo-inositol (mI), lipids (Lip) and lactate (Lac) were identified and ratios of NAA/Cr, Cho/Cr, mI/Cr, Lip/Cr, Lac/Cr calculated. Significant increases in Cho/Cr and Lip/Cr were noted. No abnormality was found in mean NAA/Cr and Lac/Cr, but in four patients there was a decreased NAA peak; mI/Cr ratio was slightly increased. Although the spectroscopic profile in patients with neuroborreliosis seems to be nonspecific, MRS might be useful for assessing tissue damage of the central nervous system. (orig.)
Availability note (English)
Available from: http://dx.doi.org/10.1007/s00234-002-0851-6Additional details
Identifiers
Publishing Information
- Journal Title
- Neuroradiology
- Journal Volume
- 46
- Journal Issue
- 1
- Journal Page Range
- p. 26-30
- ISSN
- 0028-3940
- CODEN
- NRDYAB
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 35022754
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CENTRAL NERVOUS SYSTEM; CHOLINE; CHROMIUM; CREATINE; LACTATES; LIPIDS; NERVOUS SYSTEM DISEASES; NMR IMAGING; PATIENTS; PROTONS; SPECTROSCOPY
- Descriptors DEC
- ALCOHOLS; AMINES; AMINO ACIDS; AMMONIUM COMPOUNDS; BARYONS; CARBOXYLIC ACID SALTS; CARBOXYLIC ACIDS; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; ELEMENTARY PARTICLES; ELEMENTS; FERMIONS; HADRONS; HYDROXY COMPOUNDS; LIPOTROPIC FACTORS; METALS; NERVOUS SYSTEM; NUCLEONS; ORGANIC ACIDS; ORGANIC COMPOUNDS; QUATERNARY COMPOUNDS; TRANSITION ELEMENTS