Clinical evaluation of partial splenic embolization on primary hepatic cancer with portohypertension

Objective: To evaluate the clinical efficiency of partial splenic embolization on portal hypertension patients of hepatocellulocarcinoma (HCC). Methods: 110 patients of hepatocellulocarcinoma with portohypertension were treated with 1-3 times of TACE, and partial splenic embolization, with PVA of 355-500 μm injecting into the arteries of inferior splenic pole. In order to control the area of splenic embolization, multi-embolizations were done according to the various conditions. Results: 172 times of embolization were performed in 110 patients involving 134 times of fever lasting for 3-30 days and 126 times of bellyache with 27 times appealing for morphine. Treatable hydrothorax appeared in six, and no serious complications occurred. The area of embolization covered 30%-60%. WBC and BPC counts were increased after the 24 hour (P<0.05) and the number of cases with normal WBC and BPC count were 67 and 82 respectively after three months. The improvements on appetite, vigor and remission of varix were fruitful. Conclusions: Partial splenic embolization has the effect of increasing blood cell counts and elevating immunity and improving living quality, in HCC patients with portohypertension