Published February 1980 | Version v1
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Quantitative study of pulmonary lesions and epithelial proliferation following inhalation of 239PuO2 in rats

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Description

Morphometric analyses of lung parenchyma exposed to 239PuO2 indicated a volumetric increase in pulmonary fibrosis, epithelial metaplasia, and neoplasia with increasing time after exposure. Metaplastic and neoplastic lesions usually occupied less than 1% of the total lung volume

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Additional details

Publishing Information

Imprint Title
Pacific Northwest Laboratory annual report for 1979 to the DOE Assistant Secretary for Environment. Part 1. Biomedical Sciences
Journal Page Range
p. 111-113.
Report number
PNL--3300(Pt.1)

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
11558582
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
CARCINOGENESIS; CELL PROLIFERATION; DELAYED RADIATION EFFECTS; EPITHELIUM; EXPERIMENTAL DATA; FIBROSIS; INHALATION; ISOLATED VALUES; LUNGS; MORPHOLOGICAL CHANGES; NEOPLASMS; PLUTONIUM OXIDES; PLUTONIUM 239; RATS; TOXICITY; TRACER TECHNIQUES; TRITIUM
Descriptors DEC
ACTINIDE COMPOUNDS; ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CHALCOGENIDES; DATA; DATA FORMS; DISEASES; EVEN-ODD NUCLEI; HEAVY NUCLEI; HYDROGEN ISOTOPES; INFORMATION; INTAKE; ISOTOPE APPLICATIONS; ISOTOPES; LIGHT NUCLEI; MAMMALS; NUCLEI; NUMERICAL DATA; ODD-EVEN NUCLEI; ORGANS; OXIDES; OXYGEN COMPOUNDS; PATHOGENESIS; PATHOLOGICAL CHANGES; PLUTONIUM COMPOUNDS; PLUTONIUM ISOTOPES; RADIATION EFFECTS; RADIOISOTOPES; RESPIRATORY SYSTEM; RODENTS; TISSUES; TRANSURANIUM COMPOUNDS; VERTEBRATES; YEARS LIVING RADIOISOTOPES