Clinical value of serum level of insulin-like growth factor-1 diagnosis and treatment for gastric and colorectal cancer
Creators
- 1. Dept of Surgery, the First Hospital Affiliated to Soochow University, Suzhou (China)
Description
Objective: To explore the clinical value of the serum levels of insulin-like growth factor-1 (IGF-1) in patients with gastric and colorectal cancer. Methods: IGF-1 was measured by radio-immunoassay in 26 untreated patients and 20 treated patients with gastric and colorectal cancer in 26 healthy subjects and 20 patients with benign gastrointestinal diseases respectively. CEA and CA199 were measured by chemiluminescence immunoassay. One-way analysis of variance and ROC curve analysis were used with SPSS statistical package for windows version 16. Results: Serum IGF-1 level in the untreated malignant group was (587.38±385.25) ng/ml and was significantly higher than those in the treatment group and the control group (P<0.01). Conclusion: Serum levels of IGF-1 can be used as an indicator for early diagnosis and follow-up for gastric and colorectal cancer. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Soochow University. Medical Science Edition
- Journal Volume
- 31
- Journal Issue
- 4
- Journal Page Range
- p. 642-644
- ISSN
- 1673-0399
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 46088029
- Subject category
- RADIOLOGY AND NUCLEAR MEDICINE;
- Quality check status
- Yes
- Descriptors DEI
- ANTIGENS; BLOOD SERUM; CARCINOEMBRYONIC ANTIGEN; CARCINOMAS; DIAGNOSIS; GASTROINTESTINAL TRACT; GLYCOPROTEINS; GROWTH FACTORS; INSULIN; NEOPLASMS; PATIENTS; RADIOIMMUNOASSAY;
- Descriptors DEC
- ANTIGENS; BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; CARBOHYDRATES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; HORMONES; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MITOGENS; NEOPLASMS; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SACCHARIDES; TRACER TECHNIQUES;
Optional Information
- Notes
- 1 tabs., 9 refs.