Restoration of Respiratory Gases and Acid-base Balance of Blood of Gamma Irradiated Rats Through Bone Marrow Transplantation
- 1. Department of Zoology-Faculty of Science, Cairo Univeristy, (Egypt)
- 2. National Centre for Radiation Research and Technology, Cairo, (Egypt)
Description
The present investigation aimed at elucidating the role played by bone marrow transplantation as a biological treatment against the deleterious effect of ionizing radiation. The parameters tested were PO2; PCO2; TCO2 and acid base balance encountering pH and (HCO3) in blood. Investigations were conducted 1,3,7,14 and 21 days post whole body gamma exposure at the dose levels 2 and 6 Gy. The data obtained showed highly significant changes in all tested parameters after whole body gamma irradiation. A higher depressant effect was more pronounced after exposure to higher radiation dose. Bone marrow transplantation to irradiated rats resulted in partial restoration or the radiation induced changes in both PO2 and PCO2 as recorded on the first week post treatment and succeeded to ameliorate the radiation induced changes in pH values and (HCO3) in blood
Additional details
Publishing Information
- Journal Title
- Egyptian Journal of Radiation Sciences and Applications
- Journal Volume
- 13
- Journal Issue
- 1
- Journal Page Range
- p. 37-48
- ISSN
- 1110-0303
INIS
- Country of Publication
- Egypt
- Country of Input or Organization
- Egypt
- INIS RN
- 31045915
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- BIOLOGICAL EFFECTS; BLOOD; BONE MARROW; GAMMA RADIATION; IONIZING RADIATIONS; RADIATION DOSES; RATS; RESPIRATORY SYSTEM
- Descriptors DEC
- ANIMAL TISSUES; ANIMALS; BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; DOSES; ELECTROMAGNETIC RADIATION; HEMATOPOIETIC SYSTEM; IONIZING RADIATIONS; MAMMALS; MATERIALS; ORGANS; RADIATIONS; RODENTS; VERTEBRATES