Published January 2000 | Version v1
Journal article Metadata-only

Cholinergic regulation of electrical physiology activity of cardio myocytes after prolonged gamma-irradiation

Creators

  • 1. Inst. radyyabiyalogii, Natsyyanal'naya akadehmiya navuk Belarusi, Minsk (Belarus)

Description

I was studied the effects of prolonged irradiation of rats in dose 0.5 Gy at bio electric activity of their isolated hearts. The experiments were conducted on 10, 30, 90 and 180 days after cessation of irradiation. The cholinergic regulation of heart was investigated by means of agonist of M-choline receptors carbacholine. It was found that prolonged gamma-irradiation in low dose decreased the amplitude and duration of action potentials of myocardium cells, increased the quantity of arrhythmia. The reaction of cardio myocytes at the stimulation of M-cholinergic receptors was decreased in irradiated animals

Additional details

Additional titles

Original title (Russian)
Холинергическая регуляция электрофизиологической активности кардиомиоцитов после пролонгированного гамма-облучения

Publishing Information

Journal Title
Vestsi Natsyyanal'naj Akadehmii Navuk Belarusi. Seryya Biyalagichnykh Navuk
Journal Volume
1
Journal Page Range
p. 70-73
ISSN
1029-8940

INIS

Country of Publication
Belarus
Country of Input or Organization
Belarus
INIS RN
31033319
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CARDIOVASCULAR AGENTS; CHRONIC IRRADIATION; GAMMA RADIATION; HEART; LABORATORY ANIMALS; LOW DOSE IRRADIATION; POST-IRRADIATION EXAMINATION; RATS; RECEPTORS
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BODY; CARDIOVASCULAR SYSTEM; CHRONIC EXPOSURE; DRUGS; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES

Optional Information

Notes
16 refs., 1 fig.