Published January 1999 | Version v1
Journal article

Intracranial leiomyosarcoma in a patient with AIDS

  • 1. Johns Hopkins Medical Institutions, Baltimore, MD (United States). Dept. of Pathology
  • 2. Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, MD (United States)
  • 3. Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD (United States)
  • 4. Department of Radiology, Johns Hopkins Medical Institutions, Baltimore, MD (United States)

Description

We report an intracranial leiomyosarcoma in the pontine cistern of a 34-year-old woman infected with the human immunodeficiency virus (HIV). The clinical, radiological and pathological data are reviewed. The tumor was Epstein-Barr virus (EBV) positive by in situ hybridization. This case emphasizes that smooth muscle neoplasms arising in the setting of immunocompromise can occur intracranially, and corroborates a hypothesis that EBV coinfection may have a role in development of these tumors. (orig.) (orig.)

Additional details

Publishing Information

Journal Title
Neuroradiology
Journal Volume
41
Journal Issue
1
Journal Page Range
p. 35-39
ISSN
0028-3940
CODEN
NRDYAB

Optional Information

Notes
With 6 figs., 22 refs.