Cerebral metabolic data obtained by positron emission tomography in physiological aging. A review of the literature
Description
Following a summary of the general principles and limitations of metabolic measurements by positron emission tomography and of the different indices used to interpret the data, the authors review the results of published studies on physiological aging. Globally, with strict inclusion criteria absolute metabolic values at rest and under partial sensorial deprivation are little or not modified by age. In contrast, functional interactions between regions, as deduced from metabolic intercorrelations, are perhaps different in elderly people. In any case, positron emission tomography seems to discriminate between normal aging and different patterns of pathological aging. Technical improvements, more refined neuropsychological correlations and the use of dynamic activation paradigms will no doubt provide, in the future, a better definition of normal and pathological aging as positron tomography
Abstract (French)
Apres avoir rappele les principes generaux et les limites des mesures metaboliques en tomographie d'emission par positons, de meme que les differents indices utilises pour exploiter les donnees, les auteurs rapportent les resultats de la litterature concernant le vieillissement physiologique. Dans l'ensemble, si les criteres d'inclusion sont stricts, les valeurs metaboliques absolues en condition de repos et de deprivation sensorielle partielle ne semblent pas ou peu modifiees par l'age. En revanche, les interactions fonctionnelles entre regions, deduites des intercorrelations metaboliques, sont peut-etre differentes chez le sujet age. Dans tous les cas, la tomographie d'emission par positons semble discriminative entre vieillissement normal et differents cadres du vieillissement pathologique. Les ameliorations techniques, l'affinement des correlations neuropsychologiques et l'utilisation de paradigmes dynamiques d'activation permettront certainement a l'avenir de mieux cerner par la tomographie d'emission par positons, vieillissement normal et pathologiqueAdditional details
Additional titles
- Original title (French)
- Donnees metaboliques cerebrales en tomographie d'emission par positons au cours du viellissement physiologique. Revue de la litterature
Publishing Information
- Journal Title
- Presse Med.
- Journal Volume
- 16
- Journal Issue
- 23
- Series
- Presse Med.
- Journal Page Range
- 1159-1162
- ISSN
- 0032-7867
- CODEN
- PRMEA
Conference
- Title
- 2. International symposium on cerebral ischemia and Alzheimer disease.
- Dates
- 3-4 Oct 1986.
- Place
- Madrid (Spain).
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 19001777
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- AGE DEPENDENCE; BIOLOGICAL FUNCTIONS; BRAIN; DYNAMIC FUNCTION STUDIES; METABOLISM; PATHOLOGICAL CHANGES; PHYSIOLOGY; POSITRON COMPUTED TOMOGRAPHY; REVIEWS
- Descriptors DEC
- BODY; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DISEASES; DOCUMENT TYPES; EMISSION COMPUTED TOMOGRAPHY; NERVOUS SYSTEM; ORGANS; TOMOGRAPHY