Filters
Results 1 - 10 of 12120
Results 1 - 10 of 12120.
Search took: 0.037 seconds
Sort by: date | relevance |
AbstractAbstract
No abstract available
Primary Subject
Source
3. congress of the Hungarian Society of Nuclear Medicine; Budapest (Hungary); 15 - 17 Sep 1982; Published in summary form only.
Record Type
Journal Article
Literature Type
Conference
Journal
Izotoptechnika; ISSN 0004-7201;
; v. 25(2); p. 179

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Kosinov, A.; Kotelnikova, O.
Conversion in the framework of international collaboration. Proceedings1996
Conversion in the framework of international collaboration. Proceedings1996
AbstractAbstract
[en] Main problems which should be solved: - To create the new highly productive recombinant GENI stain-producer - To select the medium and cultivation's conditions for stain-producer. - To elaborate the separation and purification GENI technology. In order to create the new GENI stain-producer we need significantly change the separation and purification's technology which was elaborated according to traditional method before. The separation and purification GENI's technology demand the industrial methods utilization, such as: ultrafiltration, high-and-low pressures chromatography. Besides, the utilization of recombinant micro-organisms, required for to obtain the medicinal preparations, places a constraint on the quality controls ready made product which should be in conformity with following conditions: high trustworthiness, reproducibility and sensitivity. In this connection, we need to perform a series of the work concerning with analytic controls methods of production and substance preparations technology. To create the separation and purification GENt technology on the highly productive recombinant GENI Stain-producers base. To put in an application in order to patient this new stain. The results of these works will be base for to prepare the normative-technical documents concerning with GENI substances production. Also, we will make the initial data and plan required for to project the GENI substances production. This work will be performed without foreign partner's participation
Primary Subject
Source
Akhmetov, T.; Vagin, S.; Urezchenko, V. (eds.); Ministry of Science Academy of Science of the Republic of Kazakhstan (Kazakhstan); International Science and Technology Center (Kazakhstan); National Nuclear Center of the Republic of Kazakhstan (Kazakhstan); 357 p; 1996; p. 11; International seminar 'Conversion in the framework of international collaboration'; Almaty (Kazakhstan); 22-26 Oct 1996; Russian version of this document is also included as part of this report
Record Type
Miscellaneous
Literature Type
Conference
Report Number
Country of publication
Reference NumberReference Number
Related RecordRelated Record
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] It was reported that the a-helix of protein molecules could be destroyed when they were exposed to the electromagnetic field (EMF) and finally the signal transduction could be affected. To study this effect, one signal molecule, insulin, was exposed to electromagnetic fields at different combinations of the field strength, repetition rate and exposure time. For the first time, structural biology approach was used to detect the EMF effect. The results of a series of measurements on the interaction of electromagnetic fields with insulin in vitro are described. Under our experimental conditions, no effects of electromagnetic field exposure were observed on the molecular conformation. (authors)
Primary Subject
Secondary Subject
Source
3 figs., 1 tabs., 28 refs.
Record Type
Journal Article
Journal
Nuclear Science and Techniques; ISSN 1001-8042;
; v. 22(3); p. 134-138

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Cantwell, Cara T; Wei, Pinghung; Ziaie, Babak; Rao, Masaru P, E-mail: mprao@engr.ucr.edu2014
AbstractAbstract
[en] While MEMS-based transdermal drug delivery device development efforts have typically focused on tightly-integrated solutions, we propose an alternate conception based upon a novel, modular drug reservoir approach. By decoupling the drug storage functionality from the rest of the delivery system, this approach seeks to minimize cold chain storage volume, enhance compatibility with conventional pharmaceutical practices, and allow independent optimization of reservoir device design, materials, and fabrication. Herein, we report the design, fabrication, and preliminary characterization of modular reservoirs that demonstrate the virtue of this approach within the application context of transdermal insulin administration for diabetes management. (technical note)
Primary Subject
Source
Available from http://dx.doi.org/10.1088/0960-1317/24/11/117001; Country of input: International Atomic Energy Agency (IAEA)
Record Type
Journal Article
Journal
Journal of Micromechanics and Microengineering. Structures, Devices and Systems; ISSN 0960-1317;
; CODEN JMMIEZ; v. 24(11); [6 p.]

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Yajnik, C.S.; Yudkin, J.S.; Shetty, P.S.; Kurpad, A.
Co-ordinated research project on application of nuclear techniques in the prevention of degenerative diseases (obesity and non-insulin dependent diabetes) in ageing1999
Co-ordinated research project on application of nuclear techniques in the prevention of degenerative diseases (obesity and non-insulin dependent diabetes) in ageing1999
AbstractAbstract
[en] There is a growing epidemic of insulin resistance syndrome (IRS) in Indians. We postulate that increased susceptibility of the urban Indians to insulin resistance is a result of a tendency to increased fat deposition from the time of intrauterine life (thrifty phenotype), exaggerated in the urban environment by a positive energy balance. The pro-inflammatory cytokines secreted by the inflammatory cells as well by the adipose tissue could aggravate insulin resistance and endothelial damage and therefore, increase the susceptibility to type 2 diabetes and coronary heart disease (CHD) independent of the previously proposed glucose fatty acid cycle mechanism. In a preliminary study, we propose to make detailed measurements of the proposed mechanisms in a selected population from 3 geographical locations in and near the city of Pune, India and also validate simple 'epidemiologic' measurements of body composition with 'reference' measurements. One hundred men (30 to 50y) each from the three geographical locations (rural, urban slum-dwellers and urban middle class in Pune) will be studied for: (i) Body composition: Anthropometric and bioimpedance measurement of total body fat (to be calibrated against deuterated water in 30 subjects from each location), and muscle mass by anthropometry and urinary creatinine excretion; (ii) Body fat distribution by subscapular- triceps ratio, waist-hip ratio; (iii) Metabolic: Glucose tolerance and insulin resistance variables (insulin, lipids, NEFA) and leptin; (iv) Endothelial markers: e-Selectin and von Willebrand Factor (vWF); (v) Inflammatory markers and pro-inflammatory cytokines: C-reactive protein (CRP), Interleukin-6 (IL-6) and tumour necrosis factor (TNF- α); (vi) Energy Balance: Assessment of nutritional intake (calories, carbohydrates, proteins and fats, n3 and n6 fatty acids) and physical activity by a questionnaire. Insulin resistance variables, endothelial markers, cytokines and obesity parameters will be compared in the 3 groups. Energy intake and physical activity will be related to obesity parameters and n3 and n6 fatty acid intake will be related to inflammatory markers. Multivariate analysis will be used to explore the independent contributions of levels of circulating cytokines and of obesity to insulin resistance syndrome variables and endothelial markers, controlling for place of residence. (author)
Primary Subject
Secondary Subject
Source
International Atomic Energy Agency, Section of Nutritional and Health-Related Environmental Studies, Vienna (Austria); 95 p; 1999; p. 38-43; 1. research co-ordination meeting on co-ordinated research project on application of nuclear techniques in the prevention of degenerative diseases (obesity and non-insulin dependent diabetes) in ageing; Vienna (Austria); 3-7 May 1999; 24 refs, 1 tab
Record Type
Report
Literature Type
Conference
Report Number
Country of publication
Reference NumberReference Number
Related RecordRelated Record
INIS VolumeINIS Volume
INIS IssueINIS Issue
Benhidour, A.E.K.; Bessaih, Z.; Khalfoun, B.
Developments in radioimmunoassay and related procedures1992
Developments in radioimmunoassay and related procedures1992
AbstractAbstract
[en] Thyroid hormones (T3 et T4) were coupled to bovine serum albumin (BSA) with glutaraldehyde in a two stage reaction. The different molecules applied at each stage of the coupling procedure were studied by UV-visible spectrophotometry. The coupling ratios of T3/BSA and T4/BSA were respectively 23 and 8. The electrophoretic motility of the conjugates in one band indicated that the products developed were homogeneous. Polyclonal antibodies were produced by rabbit immunizations with intradermal injections of the thyroid hormone immunogens emulsified in complete Freund's adjuvant. The antibodies developed have high titre and specificity. Thus, they could easily be used in the development of immunoassay procedures for the determination of the total thyroid hormones or of the free fractions. (author). 12 refs, 2 figs
Primary Subject
Source
International Atomic Energy Agency, Vienna (Austria); World Health Organization, Geneva (Switzerland); Proceedings series; 601 p; ISBN 92-0-000392-3;
; 1992; p. 219-223; IAEA; Vienna (Austria); International symposium on radioimmunoassay and related procedures: Perspectives in developing countries; Vienna (Austria); 26-30 Aug 1991; IAEA-SM--324/14; ISSN 0074-1884; 


Record Type
Book
Literature Type
Conference
Country of publication
Reference NumberReference Number
Related RecordRelated Record
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] The results of a comparative evaluation of seven immunometric TSH kits are presented. These include data on reproducibility, sensitivity, precision, bias, parallelism, cross reactivity and a clinical assessment of the kits. It was concluded that five of the kits have the potential to meet the high sensitivity requirements for clinical diagnostic application and particular aspects of performance of each of these kits are presented which may help in the selection of a method appropriate to local circumstances. (UK)
Primary Subject
Record Type
Journal Article
Journal
Communications in Laboratory Medicine; ISSN 0267-3320;
; v. 2(2); p. 49-55

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Nielsen, L.
Stanford Linear Accelerator Center, Menlo Park, CA (United States); Stanford Synchrotron Radiation Lab. (United States). Funding organisation: USDOE Office of Science (United States)2001
Stanford Linear Accelerator Center, Menlo Park, CA (United States); Stanford Synchrotron Radiation Lab. (United States). Funding organisation: USDOE Office of Science (United States)2001
AbstractAbstract
No abstract available
Primary Subject
Source
SLAC-REPRINT--2001-247; AC03-76SF00515
Record Type
Journal Article
Journal
Biochemistry (Easton); ISSN 0006-2960;
; (1Jan2001issue); [10 p.]

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Short communication
Original Title
Wartosc oznaczania FT3 w rozpoznawaniu nadczynnosci tarczycy
Primary Subject
Source
4. Scientific Congress of the Polish Society of Nuclear Medicine; 4. Zjazd Naukowy Polskiego Towarzystwa Medycyny Nuklearnej; Cracow (Poland); 26-29 May 1994
Record Type
Journal Article
Literature Type
Conference
Journal
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Ivanyi, Juraj
Proceedings of the 5. International symposium on radioimmunology, Lyon, 9-11 April 19811981
Proceedings of the 5. International symposium on radioimmunology, Lyon, 9-11 April 19811981
AbstractAbstract
No abstract available
Primary Subject
Source
Lyon-1 Univ., 69 (France); 108 p; 1981; p. 80; Faculte de Pharmacie; Lyon, France; 5. International symposium on radioimmunology; Lyon, France; 9 - 11 Apr 1981; Available from Centre de Medecine Nucleaire, F69394 Lyon Cedex 3 (France); Published in summary form only.
Record Type
Book
Literature Type
Conference
Country of publication
Reference NumberReference Number
Related RecordRelated Record
INIS VolumeINIS Volume
INIS IssueINIS Issue
1 | 2 | 3 | Next |