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[en] Combinatorial chemistry is a rapid and inexpensive technique for the synthesis of hundreds of thousands of organic compounds of potential medicinal activity. In the past few decades a large number of combinatorial libraries have been constructed, and significantly supplement the chemical diversity of the traditional collections of the potentially active medicinal compounds. Solid phase synthesis was used to enrich the combinatorial chemistry libraries, through the use of solid supports (resins) and their modified forms. Most of the new libraries of compounds appeared recently, were synthesized by the use of solid-phase. Solid-phase combinatorial chemistry (SPCC) is now considered as an outstanding branch in pharmaceutical chemistry research and used extensively as a tool for drug discovery within the context of high-throughput chemical synthesis. The best pure libraries synthesized by the use of solid phase combinatorial chemistry (SPCC) may well be those of intermediate complexity that are free of artifact-causing nuisance compounds. (author)
[en] In recent decades, electrospinning using a molten poly ( ε -caprolactone) resin has gained attention for creating fibrous tissue scaffolds. The topography and diameter control of such electrospun microfibers is an important issue for their different applications in tissue engineering. Charge density, initial nozzle-exit-channel cross-sectional area, nozzle to collector distance, viscosity, and processing temperature are the most important input parameters that affect the final electrospun fiber diameters. In this paper we will show that the effect of nozzle-exit-channel shape is as important as the other effective parameters in a resultant fiber diameter. However, to the best of our knowledge, the effect of nozzle-exit-channel shapes on a resultant fiber diameter have not been studied before. Comparing rectangular and circular nozzles with almost the same exit-channel cross-sectional areas in a similar processing condition showed that using a rectangular nozzle resulted in decreasing final fiber diameter up to 50%. Furthermore, the effect of processing temperature on the final fiber topography was investigated. (paper)
[en] In several industrial fields, epoxy resin is widely used as an adhesive for co-curing and manufacturing various structures. Controlling the manufacturing process is required for ensuring robust bonding performance and the stability of the structures. A fiber optic sensor is suitable for the cure monitoring of epoxy resin owing to the thready shape of the sensor. In this paper, a fiber Bragg grating (FBG) sensor was applied for the cure monitoring of epoxy resin. Based on the experimental results, it was demonstrated that the FBG sensor can monitor the status of epoxy resin curing by measuring the strain caused by volume shrinkage and considering the compensation of temperature. In addition, two types of epoxy resin were used for the cure-monitoring; moreover, when compared to each other, it was found that the two types of epoxy had different cure-processes in terms of the change of strain during the curing. Therefore, the study proved that the FBG sensor is very profitable for the cure-monitoring of epoxy resin
[en] In Archaeometry, the collaboration among different specialists can be very useful to solve problems of authentication and to characterize the artworks. This cooperation is also recommended in radiocarbon dating. Before dating, for example, it is important to be aware of possible restorations undergone by the artworks and, in particular, which products have been used, since they may represent a source of contamination altering the obtained date. In fact, these products are generally organic compounds, thus representing an addition of exogenous carbon, which must be completely removed. In this paper, the case of the removal of synthetic resins will be discussed. The issue of contamination by synthetic resins will be presented using two case studies: the wooden frame of a Trittico by Ambrogio Lorenzetti and a painting on canvas of the first decades of the XX century.
[en] Application of crosslinking resins is one of the effective methods used for improving the dimensional stability of cotton knitted fabrics. However, such an application often results in severe deterioration in the bursting strength of the treated fabrics. This study was undertaken for modeling and optimization of the shrinkage control and bursting strength of Lacoste Pique cotton knitted fabrics, using response surface methodology. A central composite experimental design was used to find out the optimum resin and softener concentrations along with the best curing time for maximum shrinkage control with minimum possible loss in the fabric bursting strength. (author)
[en] This book introduces story of an inventor, Jang, Yeong Sil, Screening of Jang, Yeong Sil award and prize-winning companies and titles, which are high flow blend resin by LG chemical company, lithium-ion polymer battery for MP3P by Samsung SDI Inc, tower mounted amplifier by ACE technology Inc, intelligent public access defibrillator by CU medical Inc, contrast enhanced phosphor by LG Inc, solid state drive for auxiliary memory by MTRON storage technology Co. LTD, and Selicion by Samsung fine chemistry, and new era of development of scientific technology.
[en] Y 90 resin microsphere radioembolization is used to treat inoperable hepatic tumors. After injection of Y 90 resin microsphere, the only method to visualize the distribution of Y 90 is the scintigraphic imaging of bremsstrahlung radiation. The purpose of this study was to evaluate the characteristics and usefulness of bremsstrahlung imaging in Y 90 resin microsphere treatment. Twenty patients (22 administrations) underwent intra arterial Y 90 resin microsphere treatment. For pretreatment planning, images of Tc 99m albumin macroag gregate (MAA) arterial injection and hepatic contrast angiography were obtained. Post treatment bremsstrahlung images were taken and compared with pre treatment images. The extrahepatic activity was evaluated on bremsstrahlung images. To correlate the size and vascularity of the tumors with tumor visualization on bremsstrahlung images, the individual tumors were grouped according to visualization on each image and compared with one another by size and tumor to normal ratio. All post therapeutic bremsstrahlung images showed similar contours of the liver with pre treatment angiography. No extrahepatic activity was seen in all cases. The visualized tumors on bremsstrahlung images were significantly larger than the non visualized tumors on bremsstrahlung images were significantly higher than those of the non visualized tumors. Bremsstrahlung images after intra arterial Y 90 resin microsphere treatment are useful in evaluating the intrahepatic distribution of radioisotope and detecting possible extrahepatic activity
[en] In this study, we prepared a plastic scintillator whose manufacturing process is simple and can be freely shaped. A thin plate of the plastic scintillator was manufactured using epoxy resin as a polymer. The plastic scintillator was made by mixing epoxy resin and organic scintillators under various conditions. The optimal mixture ratio to prepare the plastic scintillator was derived from the above results. Using the derived results, we made the large-area plastic scintillator which can quickly measure the contamination site and evaluated characteristics of the large-area plastic scintillator in the laboratory. A thin plate of a plastic scintillator with a simple preparation process can be freely shaped using epoxy resin and organic scintillators such as PPO and POPOP. PPO emits scintillation of light in the ultraviolet range, and POPOP is a wave shifter for moving the wavelength responsible for the PMT. The mixture ratio of PPO and POPOP was determined using their emission spectra. The optimal weight percentage of PPO and POPOP in an organic scintillator was determined to be 0.2 wt%:0.01 wt%. Based on the above results, the large-area plastic scintillator of the window size of a typical pancake-type αβ surface contamination counter was prepared. We want to evaluate the characteristics of the large-area plastic scintillator. However, there were the difficulties in evaluating characteristics of the large-area plastic scintillator. The cross-sectional area of the large-area plastic scintillator is significantly different to PMT
[en] An application of Programmable Logic Controller (PLC) in automatic control system for resin transfer in pulsed elution column is described. The design principle as well as hardware and software are also described in detail
[en] Nowadays, only crude resins are used for lacquer wares. In Myanmar lacquer ware makers have not yet used modification methods for fast drying and brightness to improve the quality as in the Japanese lacquer wares. Thus it takes about three months to season the lacquer wares. The main factor which delays the seasoning is the slow process of drying of thitsi (Myanmar lacquer), which is extracted from naturally grown Melanorrhoea usitata Wall. This paper is attempted to find ways for fast drying process. It was found that drying in the oven at 1000C is the suitable treatment for commercial scale production. (author)