[en] It is reasonable to assume that gains in detective quantum efficiency (DQE) are far better criteria for assessing the performance of hypersensitizing techniques than gains in speed. It is shown here that gains in speed can be misleading, for some methods of hypersensitization give plates of increased speed but reduced detective quantum efficiency. (author)

No abstract available

[en] Separate treatments of high temperature had considerable effect on Cl.perfrigens spores suspended in saline solution especially at 90 and 100⁰C, while 70 and 80⁰C had only slight effect on the spores viabilty. The decimal reduction times (D_T) were 33.7, 26, 4, 10.7 and 2.8 at 70, 80, 90 and 100⁰C for NCTC 8798 strain and were 45.1, 27.1, 10.2 and 4.0 for the Egyptian strain at the same degrees of temperature respectively. Heat treatment pre-irradiation at 70 and 80⁰C for 30 and 60 min decreased the viable spore numbers by about 0.5 to 3.0 log cycles, but the treatment had no effect on increasing the sensitivity of the rest spores to radiation. The decimal reduction dose (D₁₀-value) for the spores was almost the same as the control but there was a tendency to reduce the shoulder part in the radiation response curve especially when the spores were subjected to 80⁰C for 60 min. On the other hand, irradiation pre-heat treatment with doses from 1-10 KGY was sufficient to decrease the spore numbers from 0.2 to 5.0 log cycles and had a sensitizing effect on subsequently heated spores especially those exposed to 90 and 100⁰C. Meanwhile the rate of inactivation for spores exposed to 70 and 80⁰C after irradiation increased only during the first ten minutes. Thereafter, the rate of inactivation was almost the same for the non-irradiated spores. The D₁₀-values for the spores irradiated with 10 KGY were 0.77 and 0.84 minutes for NCTC 8798 strain and Egyptian strain at 100⁰C respectively and the spores were completely destroyed before 5 minutes

[en] The unique action of paclitaxel to stabilise microtubules and block cells at the radiosensitive G₂/M phase of the cell cycle, suggests it may sensitise tumours to radiotherapy. Since the use of paclitaxel may be compromised in drug resistant tumours due to drug efflux by P-glycoprotein, the ability of paclitaxel to sensitise multidrug resistant cells to radiation was examined in HL60 cells and a multidrug resistant subline, H/E8, developed by intermittent treatment with epirubicin. Poster 201. (author)

No abstract available

[en] Objective: To investigate radiosensitization effect of valproic acid (VPA) on human hepatocellular cell line SMMC-7221 and its mechanism. Methods: MTT was used to detect the proliferation and IC₅₀, of SMMC-7221 cell. FCM was adopted to analyze the changes in cell cycle and apoptosis level. Results: After co-cultured with VPA, the IC₅₀ of SMMC-7221 cell was 41.26, 9.04, 2.87 mmol/L. VPA + IR could significantly inhibit the cell proliferation, increase apoptosis level, cause G₀/G₁, phase arrest and decrease the decreased the percentages of S phrase. Conclusion: VPA could enhance the cell-killing effect of SMMC-7221 cell as a radio-sensitizer, which was associated with apoptosis and cell cycle arrest. (authors)

No abstract available

[en] A solar dryer used in Guinea for the drying of manioc is described. 3 refs, 3 figs

[en] A rotational viscosimeter type Rheotest was used to determine the apparent viscosity of heat-gelatinised suspension of irradiated and non-irradiated spices e.g. white and black pepper, nutmeg and ginger, obtained from different origin. The radiation doses were 4, 8, 16 and 32 kGy plus the zero kGy. A special storage experiment for black pepper was carried out to study the effect of storage conditions (a_w=0.25, 0.50 and 0.75, respectively) upon the rheological properties during a period of 100 days. (author) 12 refs.; 1 fig.; 2 tabs

No abstract available