Filters
Results 1 - 10 of 930
Results 1 - 10 of 930.
Search took: 0.028 seconds
Sort by: date | relevance |
AbstractAbstract
No abstract available
Primary Subject
Source
21. National Congress of the Italian Society for Nuclear Medicine and Biology; Santa Margherita Ligure (Italy); 29 May - 1 Jun 1985; Published in summary form only.
Record Type
Journal Article
Literature Type
Conference
Journal
Journal of Nuclear Medicine and Allied Sciences; CODEN JNMSD; v. 29(1-2); p. 105-106
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] The clinicopathological features and prognosis of gastric cancer in young patients are both limited and controversial. Therefore, the aim of this study was to define the clinicopathological features and prognosis of gastric cancer in young patients after curative resection. From May 2008 to December 2014, 198 young patients (age ≤ 40 years) and 1096 middle-aged patients (55 ≤ age ≤ 64 years) were enrolled in this study. The clinicopathological features and prognosis of gastric cancer in these patients were analyzed. Compared with middle-aged patients, the proportion of females, lower third tumors, tumor size less than 5 cm, poorly differentiated tumors and T1 tumors were significantly higher in young patients (all P < 0.05). The proportions of comorbidity, upper third tumors, well and moderately differentiated tumors, T4 tumors, and positive carcinoembryonic antigen (CEA), alpha fetoprotein (AFP) and carbohydrate antigen (CA) 19–9 were significantly lower in young patients (all P < 0.05). The distributions of N status and CA125 were comparable between young and middle-aged patients (all P > 0.05). The five-year overall survival rates were comparable between young patients and middle-aged patients (62.8 vs 54.7 %, P = 0.307). The tumor location, T status, N status and CA125 were independent predictors of prognosis in young patients. The overall survival of patients with tumors located in the upper or middle third was significantly lower than for those located in the lower third (60.8 vs 50.6 % vs 68.4 %, P = 0.016). The overall survival of CA125-positive patients was significantly lower than CA125-negative patients (49.0 vs 64.4 %, P = 0.001). The clinicopathological features were significantly different between young and middle-aged patients. The prognosis of gastric cancer in young patients was equivalent to that of middle-aged patients. Tumor location, T status, N status and CA125 were independent risk factors for prognosis in young patients. The online version of this article (doi:10.1186/s12885-016-2489-5) contains supplementary material, which is available to authorized users
Primary Subject
Source
Available from http://dx.doi.org/10.1186/s12885-016-2489-5; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946107; PMCID: PMC4946107; PMID: 27418046; PUBLISHER-ID: 2489; OAI: oai:pubmedcentral.nih.gov:4946107; Copyright (c) The Author(s). 2016; Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.; Country of input: International Atomic Energy Agency (IAEA)
Record Type
Journal Article
Journal
BMC cancer (Online); ISSN 1471-2407;
; v. 16; vp

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
External URLExternal URL
AbstractAbstract
No abstract available
Primary Subject
Source
9. Meeting of the autonomous nuclear medicine section of the Italian Radiology Association; Bologna (Italy); 2-6 May 1989; Published in summary form only.
Record Type
Journal Article
Literature Type
Conference
Journal
Journal of Nuclear Medicine and Allied Sciences; CODEN JNMSD; v. 33(2); p. 227-228
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Primary Subject
Source
9. Meeting of the autonomous nuclear medicine section of the Italian Radiology Association; Bologna (Italy); 2-6 May 1989; Published in summary form only.
Record Type
Journal Article
Literature Type
Conference
Journal
Journal of Nuclear Medicine and Allied Sciences; CODEN JNMSD; v. 33(2); p. 67
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] The results of investigation into the behaviour of carcinoembryonic antigen (CEA) at different forms of malignant neoplasms of a patient are presented: stomach cancer, rectum and colon intestine cancer, breast, liver and lungs cancer, and other localizations of cancer. It is shown that the results of the radioimmunoassay of the CRA level can ensure earlier discovery of tumor progress, its relapse and estimation of therapy efficiency
Original Title
Rakovo-ehmbrxonal'nyj antigen v onkologii
Primary Subject
Record Type
Journal Article
Journal
Meditsinskaya Radiologiya; ISSN 0025-8334;
; v. 28(8); p. 69-76

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Primary Subject
Source
21. National Congress of the Italian Society for Nuclear Medicine and Biology; Santa Margherita Ligure (Italy); 29 May - 1 Jun 1985; Published in summary form only.
Record Type
Journal Article
Literature Type
Conference
Journal
Journal of Nuclear Medicine and Allied Sciences; CODEN JNMSD; v. 29(1-2); p. 33-34
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Full text: Objective: To assess and compare the overall value of pleural fluid CEA and CYFRA 21-1 in differential diagnosis of pleural effusions with a meta-analysis. Methods: All the English and Chinese published studies for differential diagnosis of pleural effusions by pleural fluid CEA and CYFRA 21-1 were collected. Methodological quality of the included studies was then evaluated. Pooled sensitivity and specificity were calculated, the threshold effect and the possible sources of heterogeneity were also analyzed. SROC (summary receiver operating characteristic) was used to compare the differential diagnostic ability of pleural fluid CEA and CYFRA 21-1. Results: 19 studies were included in the meta-analysis, with a total of 3228 subjects. Pooled sensitivity and specificity of CEA and CYFRA 21-1 were 45.9%(43.2%- 48.5%),97.0%(96.0%-97.8%) and 47.3%(44.0%- 50.6%),91.8%(89.5%-93.7), respectively. Both CEA and CYFRA 21-1 have a threshold effect, the main source of heterogeneity was from variable assay methods. AUC (area under the curve) of CEA and CYFRA 21-1 were 0.7691 and 0.8213, respectively. There was no statistical significance between the AUC of CEA and CYFRA 21-1 (p>0.05). Conclusion: Both CEA and CYFRA 21-1 have good performance at differential diagnosis of pleural effusion, while compared with CEA, CYFRA 21-1 has no advantage. (author)
Primary Subject
Source
ICRT-2007: 2. international conference on radiopharmaceutical therapy; Ulaanbaatar (Mongolia); 3-7 Sep 2007; Annual conference of Asia Regional Cooperative Council for Nuclear Medicine (ARCCNM); Ulaanbaatar (Mongolia); 3-7 Sep 2007; Also available on-line: www.wjnm.org; Available in abstract form only, full text entered in this record
Record Type
Journal Article
Literature Type
Conference
Journal
World Journal of Nuclear Medicine; ISSN 1450-1147;
; v. 6(suppl.1); p. S93-S94

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Expression of the cold shock protein Y-box protein 1 (YB-1) is associated with deleterious outcome in various malignant diseases. Our group recently showed that the detection of an 18 kDa YB-1 fragment (YB-1/p18) in human plasma identifies patients with malignant diseases. We now tested the prevalence, clinical, and diagnostic value of YB-1/p18 detection in common tumors. A newly established monoclonal YB-1 antibody was used to detect YB-1/p18 by immunoblotting in plasma samples from 151 unselected tumor patients, alongside established tumor markers and various diagnostic measures, during evaluation for a cancerous disease and in follow-up studies after therapeutic interventions. Circulating YB-1/p18 was detected in 78% of patients having a tumor disease. YB-1/p18 positivity was highly prevalent in all examined malignancies, including lung cancer (32/37; 87%), breast cancer (7/10; 70%), cancer of unknown primary (CUP; 5/5, 100%) or hematological malignancies (42/62; 68%). Positivity for YB-1/p18 was independent of other routine laboratory parameters, tumor stage, or histology. In comparison to 13 established tumor markers (cancer antigens 15–3, 19–9, 72–4, and 125; carcinoembryonic antigen; cytokeratin fragments 21–1; neuron-specific enolase; alpha-fetoprotein; beta-2-microglobulin; squamous cell carcinoma antigen; thymidine kinase; tissue polypeptide antigen; pro-gastrin-releasing peptide), YB-1/p18 detection within serum samples was the most sensitive general parameter identifying malignant disorders. YB-1/p18 concentrations altered during therapeutic interventions, but did not predict prognosis. Plasma YB-1/p18 detection has a high specific prevalence in malignancies, thereby providing a novel tool for cancer screening independent of the tumor origin
Primary Subject
Source
Available from http://dx.doi.org/10.1186/1471-2407-14-33; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909385; PMCID: PMC3909385; PUBLISHER-ID: 1471-2407-14-33; PMID: 24443788; OAI: oai:pubmedcentral.nih.gov:3909385; Copyright (c) 2014 Tacke et al.; licensee BioMed Central Ltd.; This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0) (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.; Country of input: International Atomic Energy Agency (IAEA)
Record Type
Journal Article
Journal
BMC cancer (Online); ISSN 1471-2407;
; v. 14; p. 33

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
External URLExternal URL
AbstractAbstract
[en] The author is to prepare the working standard of carcinoembryonic antigen (CEA) for immunoassay and determine its potency. CEA solution of 320 μg/L was prepared from purified CEA solution of 4.6 mg/L and 1% human albumin solution buffered with 50 mmol/L sodium phosphate, pH7.4. This solution was distributed in an aliquot of 0.5 mL (160 ng per ampoule) and lyophilized. The potency of CEA working standard, in terms of present standard of CEA RIA and IRMA kits made by Chinese manufacturers and in terms of 1st IRP CEA HUMAN 73/601 supplied by WHO, has been determined. Mean immunological potency of the working standard is 163 ng per ampoule with confident limit of 159-168 ng per ampoule at 95% probability level. Test of parallelism of dose-response curve for the working standard to that for 1st IRP CEA HUMAN 73/601 has been passed. CEA working standard is suitable to the kits standard for CEA radioimmunoassay and immunoradiometric assay
Primary Subject
Record Type
Journal Article
Journal
Labeled Immunoassays and Clinical Medicine; ISSN 1006-1703;
; v. 8(1); p. 21-24

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Carcinoembryonic Antigen is one of most frequently checked tumor markers in cancer management. We performed statistical analysis with serum CEA data of 2626 persons who received regular health examination and were thought to be free of active disease to determine the cutoff values of serum CEA level in normal Korean adults and to study the factors influencing serum CEA levels in normal subjects. 1) The cutoff values of serum CEA in normal Korean adults in general were 9.28 ng/ml for men, 5.90 ng/ml for women. 2) Serum CEA level was influenced by age, present smoking history, sex, and abnormal findings in chest X ray. 3) Serum CEA level had no correlation with the history of amount of alcohol consumption or obesity. 4) Cutoff values of serum CEA in normal Korean adults were tabulated according to age, sex, and smoking history. Serum CEA level was influenced by age, sex, present smoking history and abnormal findings in chest X ray and cutoff values of serum CEA were tabulated according to age, sex, and smoking history.
Primary Subject
Source
15 refs, 3 figs, 4 tabs
Record Type
Journal Article
Journal
Journal of the Korean Radiological Society; ISSN 1738-2637;
; v. 28(3); p. 391-396

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
1 | 2 | 3 | Next |