[en] It has been suggested that an important transition in the long-run trajectory of nanotechnology development is a shift from passive to active nanostructures. Such a shift could present different or increased societal impacts and require new approaches for risk assessment. An active nanostructure 'changes or evolves its state during its operation,' according to the National Science Foundation's (2006) Active Nanostructures and Nanosystems grant solicitation. Active nanostructure examples include nanoelectromechanical systems (NEMS), nanomachines, self-healing materials, targeted drugs and chemicals, energy storage devices, and sensors. This article considers two questions: (a) Is there a 'shift' to active nanostructures? (b) How can we characterize the prototypical areas into which active nanostructures may emerge? We build upon the NSF definition of active nanostructures to develop a research publication search strategy, with a particular intent to distinguish between passive and active nanotechnologies. We perform bibliometric analyses and describe the main publication trends from 1995 to 2008. We then describe the prototypes of research that emerge based on reading the abstracts and review papers encountered in our search. Preliminary results suggest that there is a sharp rise in active nanostructures publications in 2006, and this rise is maintained in 2007 and through to early 2008. We present a typology that can be used to describe the kind of active nanostructures that may be commercialized and regulated in the future.

[en] We discuss our experience with PROOF-Lite in a context of ATLAS Collaboration physics analysis of data obtained during the LHC physics run of 2009-2010. In particular we discuss PROOF-Lite performance in virtual and physical machines, its scalability on different types of multi-core processors and effects of multithreading. We will also describe PROOF-Lite performance with Solid State Drives (SSDs).

[en] This paper reviews some recent developments in the analysis of anomalous triple and quartic vector boson couplings that have been discussed at the UK Phenomenology Workshop on Collider Physics 1999 in Durham. (author)

[en] We derive the event-by-event likelihood that allows us to extract the complete information contained in the energy, time, and direction of supernova neutrinos, and specify it in the case of SN1987A data. We resolve discrepancies in the previous literature, numerically relevant already in the concrete case of SN1987A data.

No abstract available

[en] Sandia National Laboratories has prepared a project development plan that proposes how the parties interested in the IDC Re-Engineering system will coordinate its development, testing and transition to operations.

[en] We have increased the speed and versatility of the orbit analysis process by adding a command file, or 'script' language, to RESOLVE. This command file feature enables us to automate data analysis procedures to detect lattice errors. We describe the RESOLVE command file and present examples of practical applications.

No abstract available

[en] Highlights: • We present a method for continuation of point clouds via persistence diagrams. • The key property is the differentiability of the persistence map. • The differentiability allows us to apply the Newton–Raphson method to our setting. • Our method can solve the inverse problem: from persistence diagrams to point clouds. In this paper, we present a mathematical and algorithmic framework for the continuation of point clouds by persistence diagrams. A key property used in the method is that the persistence map, which assigns a persistence diagram to a point cloud, is differentiable. This allows us to apply the Newton–Raphson continuation method in this setting. Given an original point cloud $P$, its persistence diagram $D$, and a target persistence diagram $D^{\prime }$, we gradually move from $D$ to $D^{\prime }$, by successively computing intermediate point clouds until we finally find a point cloud $P^{\prime }$ having $D^{\prime }$ as its persistence diagram. Our method can be applied to a wide variety of situations in topological data analysis where it is necessary to solve an inverse problem, from persistence diagrams to point cloud data.

[en] Over-expression of cyclooxygenase-2 (COX-2) enzyme has been reported in nasopharyngeal carcinoma (NPC). However, the prognostic significance of this has yet to be conclusively determined. Thus, from our randomized trial of radiation versus concurrent chemoradiation in endemic NPC, we analyzed a cohort of tumour samples collected from participants from one referral hospital. 58 out of 88 patients from this institution had samples available for analysis. COX-2 expression levels were stratified by immunohistochemistry, into negligible, weak, moderate and strong, and correlated with overall and disease specific survivals. 58% had negligible or weak COX-2 expression, while 14% and 28% had moderate and strong expression respectively. Weak COX-2 expression conferred a poorer median overall survival, 1.3 years for weak versus 6.3 years for negligible, 7.8 years, strong and not reached for moderate. There was a similar trend for disease specific survival. Contrary to literature published on other malignancies, our findings seemed to indicate that over-expression of COX-2 confer a better prognosis in patients with endemic NPC. Larger studies are required to conclusively determine the significance of COX-2 expression in these patients