Filters
Results 1 - 10 of 1501
Results 1 - 10 of 1501.
Search took: 0.021 seconds
Sort by: date | relevance |
Guasti de F, M.V.; Olguin R, F.
4. Symposium on nuclear chemistry, radiochemistry and radiation chemistry, University City, Mexico, 7-10 September 1982 - Review1982
4. Symposium on nuclear chemistry, radiochemistry and radiation chemistry, University City, Mexico, 7-10 September 1982 - Review1982
AbstractAbstract
No abstract available
Original Title
Elaboracion, esterilizacion y prueba biologica de un alimento para animales
Primary Subject
Source
Universidad Nacional Autonoma de Mexico, Mexico City. Centro de Estudios Nucleares; 84 p; 1982; p. 78; 4. Symposium on nuclear chemistry, radiochemistry and radiation chemistry; Mexico City (Mexico); 7-10 Sep 1982; Published in summary form only.
Record Type
Miscellaneous
Literature Type
Conference
Report Number
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Original Title
Zur antimikrobiellen Chemotherapie bei der akuten Strahlenkrankheit
Primary Subject
Source
9. meeting on clinical radiobiology and experimental radiotherapy of the GDR; Wartburg/Eisenach (German Democratic Republic); 28 Feb - 4 Mar 1983; Published in summary form only.
Record Type
Journal Article
Literature Type
Conference
Journal
Radiobiologia Radiotherapia; ISSN 0033-8184;
; v. 26(2); p. 160

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] The prediction of a response to irradiation is one of the most urgent problems in modern radiobiology. The accumulated experimental material requires the use of mathematical methods in strict succession for analysis of the regularities of prognosis. Analysis of individual radiosensitivity of animals by means of mathematical methods includes 6 stages. This approach can lay the basis for the formation of a package of applied programs to study relantionships of the system. The package aimed at a dialogue with a researcher and solving a graphic data image will enable one to determine the statistical regularities of the system behaviour
Original Title
Vozmozhnosti primeneniya matematicheskikh metodov dlya prognozirovaniya individual'noj radiochuvstvitel'nosti
Primary Subject
Record Type
Journal Article
Journal
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Budarkov, V.A.; Bakulov, I.A.; Makarov, V.V.; Chumak, R.M.
Radionuclides methods in virusology and microbiology research1990
Radionuclides methods in virusology and microbiology research1990
AbstractAbstract
[en] The distribution of microbes in the body was established using radioisotopes; it is important for the studies of the nature of disease pathogenesis. The study of the bacteria distribution and accumulation in different organs and tissues, various ways of their excretion from animal organisms allows to understand and ertablish the infections and epizootic processes. The application of radioisotopes allow to interpret the mechanism of pathogen transfer, ways of its distribution and infection of healthy animals. 383 refs
Original Title
Primenenie radionuklidov v bakteriologii i ehpizootolgii
Primary Subject
Source
168 p; 1990; p. 157-165; Ehnergoatomizdat; Moscow (USSR)
Record Type
Book
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Dodson, M.V.; Vierck, J.L.; Hausman, G.J.; Guan, L.L.; Fernyhough, M.E.; Poulos, S.P.; Mir, P.S.; Jiang, Z., E-mail: dodson@wsu.edu2010
AbstractAbstract
[en] Molecular mechanisms of peroxisome proliferator activated receptors (PPARs) are being defined rapidly, as illustrated by the volume of papers published. Much of the research is directed towards a clinical end-point/application; however, the non-homogeneous nature of adipose depots in laboratory animals is spurring similar research in domestic meat animals (such as beef cattle). Moreover, the size of adipose depots in meat animals remains an attractive feature for using them to obtain cells for PPAR research. Examination of meat-animal depot-specific PPAR moieties may provide novel information about adipocyte regulation that might be extrapolated to all animals.
Primary Subject
Source
S0006-291X(10)00414-6; Available from http://dx.doi.org/10.1016/j.bbrc.2010.02.170; Copyright (c) 2010 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)
Record Type
Journal Article
Journal
Biochemical and Biophysical Research Communications; ISSN 0006-291X;
; CODEN BBRCA9; v. 394(2); p. 241-242

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Legeay, G.; Geneste, M.; Brawers, G.
CEA Fontenay-aux-Roses, 92 (France)1965
CEA Fontenay-aux-Roses, 92 (France)1965
AbstractAbstract
[en] The preparation of the monkey for experiments is one branch of zootechny applied to laboratory animals. The construction of a monkey-house at the Saclay Nuclear Research Centre has made it possible to study the hygiene rules necessary for obtaining subjects with relatively stable biological parameters. This hygiene includes: - prophylactic treatment, because the animals received lived originally in the wild state, - a balanced diet according to modern dietetic standards, - a habitat hygiene which recreates the original living conditions of the species. The possibility of reproduction has been used as a criterion of the efficiency of the methods applied. (authors)
[fr]
La mise en condition du singe en vue de son utilisation a des fins experimentales est une branche de la zootechnie appliquee aux animaux de laboratoire. La realisation d'une singerie au CEN/SACLAY a permis d'etudier les regles d'hygiene requise pour obtenir des sujets dont les parametres biologiques soient relativement stables. L'hygiene comporte: - des soins prophylactiques car les animaux livres proviennent de capture a l'etat sauvage, - une alimentation equilibree, selon les normes modernes de la dietetique, - une hygiene de l'habitat recreant les conditions du milieu originel de l'espece. La possibilite de la reproduction a ete utilisee comme critere de l'efficacite des methodes mises en oeuvreOriginal Title
Conditionnement des primates pour l'experimentation
Primary Subject
Source
1965; 39 p; 63 refs.
Record Type
Report
Report Number
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
Lee, J. D.; Park, K. K.; Lee, M. G.; Lee, J. T.; Yoo, H. S.; Kim, E. H.; Rhim, K. J.; Kim, Y. M.; Park, K. B.; Kim, J. R.
Proceedings of the 12th KAIF/KNS annual conference1997
Proceedings of the 12th KAIF/KNS annual conference1997
AbstractAbstract
[en] Skin cancer is the most common malignant tumors in human. Therapeutic modalities of the skin cancers are local destruction, radiotherapy and surgery. External radiation therapy leads to good results, however, overall 5-6 weeks of treatment period is needed to deliver optimal radiation dose to tumors. In this study, β-emitting radionuclide, Ho-166, impregnated in a specially designed patch was utilized to superficial skin cancers and Bowen's disease for local irradiation. Methods; Animal study was employed in 10 mice with chemically induced skin tumors. Five- mm size patches containing 22.2 -72.15 MBq(0.6 - 1.95 mCi) of Ho-166 were applied to the tumor surface for 1 -2 hr. In clinical trial, patients with squamous carcinoma(n=3), basal cell carcinoma(n=1), and Bowen's disease(n=1) were treated with patches containing 273.8 - 999 MBq (7.4 - 27 mCi) of Ho-166 for 30 minutes to 1 hour. Pathologic examination was performed 4 - 7 weeks after the treatment in animal model. Skin biopsy was performed 8 weeks post-treatment in four patients. Results; Tumor destruction was seen 1 week post the treatment, however, radiation dermatitis or ulceration developed at the site of radionuclide application. Those reactions healed gradually with fibrosis or epithelialization, which was confirmed pathologically. No significant adverse reaction to radiation except subcutaneous fibrosis was found. Conclusion; Superficial skin tumors could be successfully treated by topical application of β-emitting radionuclides. (author)
Primary Subject
Source
Korea Atomic Industrial Forum Inc., Seoul (Korea, Republic of); Korean Nuclear Society, Taejon (Korea, Republic of); 808 p; Apr 1997; p. 359-366; Korea Atomic Industrial Forum Inc. and Korean Nuclear Society; Seoul (Korea, Republic of); 12. KAIF/KNS annual conference; Seoul (Korea, Republic of); 3-4 Apr 1997; Available from KAERI
Record Type
Miscellaneous
Literature Type
Conference
Country of publication
Reference NumberReference Number
Related RecordRelated Record
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Gene therapy constitutes a promising option for efficient and targeted treatment of several inherited disorders. Imaging techniques using ionizing radiation as PET or SPECT are used for non-invasive monitoring of the distribution and kinetics of vector-mediated gene expression. In this review the main reporter gene/reporter probe strategies are summarized, as well as the contribution of preclinical models to the development of this new imaging modality previously to its application in clinical arena.
[es]
La terapia génica constituye una nueva y prometedora opción para un tratamiento eficiente y dirigido de numerosas enfermedades hereditarias. Las técnicas de imagen que utilizan radiaciones ionizantes como PET o SPECT son utilizadas para la monitorización no invasiva de la distribución y la cinética de la expresión génica mediada por distintos vectores. En este resumen se explican brevemente los principales sistemas gen reportero/sonda reportera que permiten la visualización in vivo de la expresión génica, así como la aportación de los modelos preclínicos al desarrollo de esta nueva estrategia de imagen previamente a su aplicación en el ámbito clínico.Original Title
Aplicaciones de la Imagen Molecular Preclínica en Biomedicina: Terapia Génica
Primary Subject
Source
Available from http://www.sepr.es/recursos/revista/RP79/pdf/Radioproteccion-79.pdf
Record Type
Journal Article
Journal
Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
No abstract available
Original Title
Novas evidencias sobre a participacao dos ameloblastos secretores durante a maturacao do esmalte visualizados por estudo radioautografico
Primary Subject
Source
32. Annual Meeting of the Brazilian Society for the Advancement of Science; Rio de Janeiro, Brazil; 6 - 12 Jul 1980; Published in summary form only.
Record Type
Journal Article
Literature Type
Conference
Journal
Cienc. Cult. (Sao Paulo) Supl; v. 32(7); p. 591
Country of publication
LanguageLanguage
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
AbstractAbstract
[en] Inflammatory bowel diseases are lifelong disorders affecting the gastrointestinal tract characterized by intermittent disease flares and periods of remission with a progressive and destructive nature. Unfortunately, the exact etiology is still not completely known, therefore a causal therapy to cure the disease is not yet available. Current treatment options mainly encompass the use of non-specific anti-inflammatory agents and immunosuppressive drugs that cause significant side effects that often have a negative impact on patients’ quality of life. As the majority of patients need a long-term follow-up it would be ideal to rely on a non-invasive technique with good compliance. Currently, the gold standard diagnostic tools for managing IBD are represented by invasive procedures such as colonoscopy and histopathology. Nevertheless, recent advances in imaging technology continue to improve the ability of imaging techniques to non-invasively monitor disease activity and treatment response in preclinical models of IBD. Novel and emerging imaging techniques not only allow direct visualization of intestinal inflammation, but also enable molecular imaging and targeting of specific alterations of the inflamed murine mucosa. Furthermore, molecular imaging advances allow to increase our knowledge on the critical biological pathways involved in disease progression by characterizing in vivo processes at a cellular and molecular level and enabling significant improvements in the understanding of the etiology of IBD. This review presents a critical and updated overview on the imaging advances in animal models of IBD. Our aim is to highlight the potential beneficial impact and the range of applications that imaging techniques could offer for the improvement of the clinical monitoring and management of IBD patients: diagnosis, staging, determination of therapeutic targets, monitoring therapy and evaluation of the prognosis, personalized therapeutic approaches.
Primary Subject
Record Type
Journal Article
Journal
Quarterly Journal of Nuclear Medicine and Molecular Imaging (Online); ISSN 1827-1936;
; v. 62(1); p. 78-100

Country of publication
Reference NumberReference Number
INIS VolumeINIS Volume
INIS IssueINIS Issue
1 | 2 | 3 | Next |