[en] Published in summary form only

[en] In this study, the decay form of ⁹⁹Mo which is supplied by KAERI had been investigated from the analysis of γ-ray energy spectrum radiating from the radioactive element ⁹⁹Mo. The γ-ray energy spectrum was obtained using NaI(T1) scintillation detector and multichannel pulse height analyser. The calibration curve and formula for γ-ray energy versus channel number were made from the two photopeaks of standard radioactive source ²²Na, 140 and 314 channel corresponding to the γ-ray energy of 511 keV and 1275 keV, respectively. The γ-ray energies from ⁹⁹Mo were detected at the same condition with the standard source, and compared with standard energies of ⁹⁹Mo. Experimental results show that the γ-ray energies from the sample are in good agreement with the values of standard source within energy error of 2 keV, which means that the ⁹⁹Mo supplied by the KAERI can be used as a standard radioactive source. (Author)

[en] The description is given of a rechargeable radioactive isotope generator having the following features: a box containing a transport shield, a shielded generator including elements for the absorption and holding of the parent isotope, an eluant tank, a first pipe causing this tank to communicate with the transport shield, a second pipe causing this transport shield to communicate with the shielded generator and a third pipe placing the shielded generator in communication with the outside of the unit. It also includes a shelf across the external front part of the unit a part of which is shielded by external components, a shielded elution flask in which the eluate is poured and a filter set at a point between the flask and the third pipe

[en] This Annex has been provided in its entirety by the University of Missouri Research Reactor as an example procedure. Alternatives to brand name products mentioned may be available. Detailed information on the special tools, equipment and reagents and procedure is given

[en] Radionuclide generators have been the main stay of diagnostic nuclear medicine and it is no exaggeration to state that the growth of nuclear medicine would not have happened to the present levels but for the availability of ⁹⁹Mo/^99mTc generator. This article provides a brief account of the various radionuclide generators currently in clinical use or which have made substantial progress or likely to be materialized in the foreseeable future to bring evolutional progress in nuclear medicine. Further, a brief outline on the regulatory challenges and impact on radionuclide generator technology with the emergence of professionally run central radiopharmacies have been provided. (author)

[en] The ability to describe in a realistic way the biokinetics of radionuclides in the human body is an important requirement in order to get a reliable dose estimation after incorporation of radioactive substances. Recent experimental data have shown the need to introduce relevant modifications to the current model of the biokinetics of molybdenum adopted by ICRP. A new series of investigations, conducted on healthy human volunteers using stable isotopes of Mo as tracers, has been undertaken in order to improve the knowledge of some of the new features outlined in the preliminary investigations. In particular, the results presented here deal with the dependence of the biokinetic parameters on the mass of Mo administered and on its content in the body. The clearance of Mo from blood plasma is not influenced by the administration of different amounts of Mo; the opposite is true for urinary excretion, which is the process adopted by the organism to regulate the body content of Mo rapidly. This fact can be of some importance in deciding a proper intervention after an accidental incorporation of Mo radionuclides. (author)

[en] A radiochemical method to isolate ⁹⁹Mo from ¹³²Te both produced in the fission of ²³⁵U has been developed. The methods is based on the formation of a cationic complex of tellerium with thiourea in acid medium which is retained (98.7 ^+- 0.5)% on a cation exchange resin (Dowex 50W-X8, 100 - 200 mesh) while (99.8 ^+- 0.05)% ⁹⁹Mo passes through it, due to the non formation of such complex in the same experimental conditions. The radionuclidic purity of the separated ⁹⁹Mo verified by using gamma spectrometry was found to be suitable for the preparation of ⁹⁹Mo - ⁹⁹ sup (m)Tc generators. The retention of ⁹⁹Mo on an alumina column as function of ph was investigated. the best pH range for this purpose was found to be between 4.0 - 4.5. the ⁹⁹Mo - ^99mTc generator was prepared. the elution of^99mTc was carried out with physiologic saline solution. The radionuclidic purity of the eluate was found suitable and the product can be used for Nuclear Medicine applications. (author)

[en] As an alternative technology of the currently available ^99mTc generator, a generator is developed by using an activated ⁹⁹Mo as the mother source of ^99mTc. In the period of 2008 ∼ 2009, the world was suffered by the short supply of ^99mTc for medical diagnosis because of the aging of the production plants in the world and no availability of an immediate solution. In this regard, it is expected to secure the supply of ^99mTc at least certain portion of the total demand for ^99mTc by developing an alternative technology such as producing ^99mTc by activated ⁹⁹Mo, cyclotron technology, etc. This research aims the development of a new ⁹⁹mTc generator to relief suffer from the short supply of the generator produced by using Fission Moly. The developed generator will act as the emergency ^99mTc resource until the ultimate solution becomes realistic. In this paper, the research progress from the basic study that has been performed during the last years will be presented

[en] Shortages of ⁹⁹Mo, the most commonly used diagnostic medical isotope, have caused great concern and have prompted numerous suggestions for alternate production methods. A wide variety of accelerator-based approaches have been suggested. In this paper we survey and compare the various accelerator-based approaches.

[en] Each of four prospective producers of molybdenum-99 says it can satisfy at least half of US demand for the short-lived substance