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[en] A retrospective analysis of 197 early glottic carcinoma treated with small field irradiation to a dose of 65 Gy is presented. The 5-year survival rate was 77.3%. Thirty-eight local failures have been obsreved, and the 5-year local control rate was 85.7%. Suspicion of extra glottic extension was the main prognostic factor. Final local control rate, taking into account the salvage treatment, was 90% at 5 years. Excellent functional results were observed. (author). 25 refs.; 3 figs.; 5 tabs
[en] This paper reports on the radiology of the pharynx. The pharynx includes the portion of the foregut located behind the nasal cavity, mouth, and larynx. It is classically divided into three segments: the uppermost segment, the nasopharynx or epipharynx, which is exclusively respiratory in function; the midportion, the oropharynx or mesopharynx, where food and air intermingle; and the lowest segment, the laryngopharynx or hypopharynx, which is concerned solely with the swallowing of food. Since the nasopharynx is exclusively respiratory in function, this discussion will be limited to the mesopharynx and hypopharynx
[en] We describe a series of three patients who had fluoroscopic-guided placement of a large-bore gastrostomy tube using a pull technique and a large snare placed via a nasogastric or orogastric tube.
[en] Based on the clinical data of a retrospective study of 659 patients with routine computed tomography of the nasopharyngeal region, a refine-ment of Ho's stage-classification for NPC is proposed with reduction in the number of overall stages without sacrificing the accuracy in pre-dicting prognosis in short term. Classifying the cervical lymph nodal metastasis into supra-clavicular (Ho's N3) and above supra-clavicular (Ho's N1+N2) and the nasopharyngeal primary into early (Ho's N1+N2n +T2o) and advanced (HO's T2p+T3+T3p) forms the conceptual back-bone of the present proposed modification of the original Ho stage-classification. Power in predicting the occurrence of distant metastases and the local failures has been enhanced by the proposed T-stage and N-stage re-grouping. Retrospective comparison between Ho's and the UICC stage-classifications showed a more even patients number distribution among the overall stages and a greater power in predicting NPC prognosis for the former. Prospective studies to compare the value of the different stage-classifications are required for recommendation of a single classification for general acceptance to facilitate comparison of treatment results between centres. (author). 24 refs.; 9 figs.; 3 tabs
[en] Nasopharyngeal carcinoma, the fifth commonest in Kenya, is discussed. The clinical presentation, duration of symptoms, histological differentiation and the treatment method are outlined. The paper discusses the problems experienced in the Department of Radiotherapy at KNH owing to insufficient facilities in the country and late presentation of the patients to the oncologists. One year local primary tumour and neck node metastases control is presented with suggestions for improving the overall results in the future. (author)
[en] Target delineation in nasopharyngeal carcinoma (NPC) often proves challenging because of the notoriously narrow therapeutic margin. High doses are needed to achieve optimal levels of tumour control, and dosimetric inadequacy remains one of the most important independent factors affecting treatment outcome.