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AbstractAbstract
[en] A radiochemical ligand binding assay for methotrexate is provided. A binder factor comprising a partially purified dihydrofolic acid reductase preparation is employed. The binder factor is conveniently prepared by homogenizing a factor containing animal organ such as liver, and extracting with isotonic saline and ammonium sulfate. A binder cofactor, NADPH2, is also employed in the binding reaction. The procedure contemplates both direct and sequential assay techniques, and it is not interfered with by vast excesses of many natural folate derivatives. 12 claims, 6 drawing figures
Primary Subject
Source
21 Sep 1976; 12 p; US PATENT DOCUMENT 3,981,983/A/
Record Type
Patent
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AbstractAbstract
[en] The principles of developing the radioecological monitoring bench mark net proposed include the regularity pattern of reference point setting, the bench mark net hierarchy, accounting for a land-tenure structure and the landscape and geochemical conditions of the radionuclide migration as well as a passport system and informational adequacy. The expression has been obtained for determining the location of sampling points
Original Title
Printsipy postroeniya repernoj tsepi radioehkologicheskogo monitoringa territorii Belorussii
Primary Subject
Record Type
Journal Article
Journal
Vestsi Akademii Navuk BSSR. Seryya Fizika-Ehnergetychnykh Navuk; ISSN 0374-4760; 
; CODEN VAFEA; (no.2); p. 5-7
; CODEN VAFEA; (no.2); p. 5-7
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AbstractAbstract
No abstract available
Primary Subject
Source
Ceskoslovenska Akademie Ved, Brno. Biofysikalni Ustav; p. 18; 1972; The bases of the biological effects of ultraviolet radiation; Brno, Czechoslovakia; 2 Oct 1972; Published in summary form only.
Record Type
Report
Literature Type
Conference
Report Number
Country of publication
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Charlton, J.C.; Glover, J.S.; Shephard, B.P.
Radiochemical Centre Ltd., Amersham (UK)1977
Radiochemical Centre Ltd., Amersham (UK)1977
AbstractAbstract
[en] This invention concerns the vessels used in radiation counting to determine radioactivity levels. These vessels prove to be particularly useful in analyses of the kind where a radioactive element or compound is separated into two phases and the radioactivity of one phase is determined. Such a vessel used in the counting of radiation includes an organic plastic substance tube appreciably cylindrical in shape whose upper end is open whilst the lower end is closed and integral with it, and an anti-radiation shield in metal or in metal reinforced plastic located at the lower end of the tube and extending along the wall of the tube up to a given height. The vessel contains a reaction area of 1 to 10 ml for holding fluid reagents
[fr]
La presente invention concerne les recipients utilises dans le comptage de rayonnements pour determiner les niveaux de radioactivite, recipients qui s'averent notamment utiles dans les analyses du genre ou un element ou compose radioactif est separe en deux phases et le niveau de radioactivite d'une phase est determinee. Un tel recipient utilisable dans le comptage de rayonnements comprend: un tube en matiere plastique organique de forme sensiblement cylindrique dont l'extremite superieure est ouverte tandis que l'extremite inferieure est fermee et solidaire de lui; un blindage anti-radiation en metal ou en matiere plastique armee de metal situe a l'extremite inferieure du tube et s'etendant sur la paroi du tube jusqu'a une hauteur uniforme; le recipient renfermant une zone de reaction de 1 a 10 ml destinee a recevoir des reactifs fluidesOriginal Title
Recipient destine au comptage de rayonnements pour determiner les niveaux de radioactivite
Primary Subject
Source
11 Feb 1977; 15 p; FR PATENT DOCUMENT 2341143/A/; Available from Institut National de la Propriete Industrielle, Paris (France); Priority claim: 13 Feb 1976, GB.
Record Type
Patent
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AbstractAbstract
No abstract available
Original Title
Dosage du cortisol plasmatique. Procede simple de partage, precedant une methode de radio-competition proteique
Primary Subject
Record Type
Journal Article
Journal
Annales d'Endocrinologie (Paris); v. 35(3); p. 223-229
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AbstractAbstract
[en] Serum protein comprising specific binding proteins such as antibodies, B12 intrinsic factor, thyroxin binding globulin and the like may be copolymerized with globulin constituents of serum by the action of ethylchloroformate to form readily packed insoluble precipitates which, following purification as by washing, are eminently suited for employment as competitive binding protein absorbents in radioassay procedures. 10 claims, no drawings
Primary Subject
Source
14 Sep 1976; 8 p; US PATENT DOCUMENT 3,980,764
Record Type
Patent
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AbstractAbstract
[en] The report includes brief description of the research and development activities under progress in the 9 scientific and technical divisions of the Centre. Many graphs and tables have been used to explain the research projects
Primary Subject
Source
1980; 67 p; Available from Atomic Energy Centre, Dacca (Bangladesh)
Record Type
Report
Literature Type
Progress Report; Bibliography
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Reference NumberReference Number
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AbstractAbstract
[en] A radioimmunoassay for a breast cancer associated antigen identified with two monoclonal antibodies (115D8/DF3) has been recently developed. The authors studied the behaviour of this new marker before using it routinely. From data of 107 normal subjects they chose a positive/negative cut-off of 31 u/ml (mean+3 SDs). High positivity rates and very high levels were found in advanced breast cancer; in primary breast cancer the CA15/3 serum levals were related to both tumor size and lymphnodal status. Low positivity rates were found in other advanced malignancies (lung, large bowel, esophagus, head and neck); however, high values were found in ovarian cancer patients. A high number of positive cases, but not very high levels, were found in a group of patients with mild or severe hepatic disease. Finally, the antigen was found in the cytosol of both breast carcinoma and, at lower levels, of normal breast tissue
Primary Subject
Source
20 refs.
Record Type
Journal Article
Journal
Journal of Nuclear Medicine and Allied Sciences; CODEN JNMSD; v. 30(1); p. 29-30
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Lamargot, J.-P.; Wanin, Maurice.
Institut de Recherches de la Siderurgie Francaise (IRSID), 78 - Saint-Germain-en-Laye1980
Institut de Recherches de la Siderurgie Francaise (IRSID), 78 - Saint-Germain-en-Laye1980
AbstractAbstract
[en] This invention falls within the area of quantitative or semi-quantitative analysis by gamma spectrometry and particularly refers to a device for bringing the samples into the counting position. The purpose of this invention is precisely to provide an automatic apparatus specifically adapted to the analysis of hard gamma radiations. To this effect, the invention relates to a gamma spectrometry analytical device comprising a lead containment, a detector of which the sensitive part is located inside the containment and additionally comprising a transfer system for bringing the analyzed samples in succession to a counting position inside the containment above the detector. A feed compartment enables the samples to be brought in turn one by one on to the transfer system through a duct connecting the compartment to the transfer system. Sequential systems for the coordinated forward feed of the samples in the compartment and the transfer system complete this device
[fr]
L'invention se situe dans le domaine de l'analyse quantitative ou semi-quantitative par spectrometrie γ et concerne plus specialement un dispositif pour amener les echantillons en position de comptage. Le but de la presente invention est precisement de fournir un dispositif automatique specifiquement adapte a l'analyse de rayonnements γ durs. A cet effet, l'invention a pour objet un dispositif d'analyse par spectrometrie γ comprenant une enceinte en plomb, un detecteur dont la partie sensible est disposee a l'interieur de l'enceinte et comprenant en outre un systeme de transfert permettant d'amener successivement les echantillons analyses en position de comptage a l'interieur de l'enceinte au-dessus du detecteur. Un magasin d'alimentation permet d'amener successivement et un par un les echantillons sur le systeme de transfert par l'intermediaire d'une cheminee reliant ce magasin au systeme de transfert. Les moyens sequentiels d'avancement coordonne des echantillons dans le magasin d'alimentation et le systeme de transfert completent ce dispositifOriginal Title
Dispositif automatique d'analyse par spectrometrie γ
Source
24 Oct 1980; 6 p; FR PATENT DOCUMENT 2452706/A/; Available from Institut National de la Propriete Industrielle, Paris (France)
Record Type
Patent
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Reference NumberReference Number
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AbstractAbstract
[en] The authors used an immunoradiometric assay for serum antigen CA-125 in a survey of 92 patients affected by epithelial ovarian carcinoma. With this assay, positive values for cut-off of 35 U/ml were found in 85% of patients with active disease. Longitudinal levels of CA-125 were in agreement with clinical course in 23 out of 26 patients monitored serially; a discordant increase occurred in the remaining 3 patients. Levels of CA-125 may aid in monitoring the disease in patients with epithelial ovarian cancer and in certain instances they may reveal recurrence several months before the corresponding clinical diagnosis
Primary Subject
Record Type
Journal Article
Journal
Journal of Nuclear Medicine and Allied Sciences; CODEN JNMSD; v. 30(1); p. 45-50
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