[en] Gamma transitions following the decay of ⁷⁵Se have been studied using a Ge(Li) detector and a NaI(Tl)-NaI(Tl) sum-coincidence spectrometer, used in conjunction with a slow-fast coincidence circuit. Two new gamma rays of energy 373.5 and 556.4 keV have been observed and confirmed in the level scheme of ⁷⁵As. Ambiguous gamma transitions of 249.2, 468.6, 542.2, and 821.6 keV energies have also been confirmed. No evidence was found for the existence of 269.0, 293.0, and 308.0 keV transitions. The accurate intensities for various transitions have been determined. (author)

[en] A cheap, easy method of introducing high specific activity Se-75 into radiopharmaceuticals is described. Se-75 selenious acid is reduced with NaBH₄ producing the nucleophile NaHSe. Using this method, a fatty acid, cholesterol, estrogen and phenethylamine are all labelled with Se-75. (U.K.)

[en] Over a period of 3 years about 1.120 parathyroid hormone assays were carried out in 527 patients. Of these, 198 (38%) showed elevated serum levels. Feedback from referring institutions, where received, indicated that primary hyperparathyroidism was confirmed surgically in 42 cases. Of these, 6 had normal parathyroid hormone levels, while 36 showed minor to substantial elevations. In 24 patients parathyroid hormone was also determined in blood samples selectively obtained from the cervical veins. The results of 16 determinations agreed well with the clinical course and the surgical findings. In the remaining 8 cases surgical reports were inadequate or unavailable. The authors conclude from this evidence that parathyroid scanning with Se₇₅ methionine appears to have no longer a place in localizing adenomas. The comparison of pre- and postoperative findings showed a mostly appreciable drop of parathyroid hormone serum levels after surgery which was consistent with the clinical course. Calcium concentrations were as high as or higher than preopoeratively in 5 cases. This appears to suggest that calcium levels have a lower diagnostic potential at least in normocalcemic cases. (Author)

[en] A retrospective study of thymus scintigraphs using selenomethionine ⁷⁵Se was made on 65 patients, 59 myasthenic and 6 presenting various mediastinal formations. Special attention was paid to highly individualized uptake centres. Certain inconsistencies often observed in practice were noted however. Selenium 75-labelled thymus scintigraphy on myasthenics was found to be difficult because of the low activities detected, the artefacts possible, the variability of the thymus and the poor condition of the patients. Carried out on 59 myasthenics it gave 23% focal images in 52 patients possessing their thymus. This fraction compares with that of the radiological anomalies observed in these patients

[en] Selenium 75 has nuclear properties very suitable for the labelling of steroids used as tracers in competition analysis. A method of preparing a selenium-labelled cortisol derivative, ⁷⁵Se methylselenoprednisolone, is described. A system based on bonding competition between plasma cortisol and ⁷⁵Se methylselenoprednisolone on transcortine was studied, the separation taking place on a Sephadex adsorbant. An early analysis with highly stable reagents was achieved

[en] The physical properties of the isotope Se-75 are introduced and there is a report on first experience with it and new working equipment (GAMMAMAT) especially matched to Se-75. (orig.)

[en] Selenium (Se) is an essential micronutrient for human health, but its deficiency may affect at least one billion people worldwide. Plants and plant-derived products transfer the soil-uptaken Se to humans through the food chain, which is hardly enough when soils have been always poor or already exhausted in bioavailable Se species. Other than agronomic approaches for enhancing Se levels in cereals, such as soil and foliar supplements, seed enrichment may be viewed as an alternative Se-biofortification technique. This study addresses the protocol for preparing Se-enriched wheat seeds, with the specific purpose of optimizing the administration of Se to the seeds prior to sowing. The first step was to soak an amount of bread-wheat seeds in an active Se solution, made with irradiated [Na₂O₄Se], and then monitoring ⁷⁵Se in periodically-retrieved samples from that original amount. To avoid losing Se to soil (after sowing), and, especially, to ensure that Se gets really absorbed into the seeds - and not just adsorbed onto them - the washing time of the seeds should be optimized as well. This was carried out by washing Se-treated seeds several times, until no significant amount of the radiotracer could be detected in the washing water. In what concerns the full optimization procedure, the overall results of the present study point to an optimum time of 48 h for soaking and 24 h for washing. (author)

No abstract available

No abstract available

[en] Published in summary form only