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AbstractAbstract
[en] Different embolic materials for portal vein embolization (PVE) were evaluated. Twenty pigs received left and median PVE. Hydrophilic phosphorylcholine, N-butyl cyanoacrylate, hydrophilic gel, and polyvinyl alcohol (PVA) particles measuring either 50-150 μm or 700-900 μm were used in five pigs each. Portography and portal vein pressure measurement were performed before, immediately after PVE, and before being euthanized at day 7. Tissue wedges from embolized, and non-embolized liver were obtained for pathology. After complete embolization, recanalization occurred at 7 days in one gel and one 700-900 PVA embolization. Post-PVE increase in portal pressure was found in all groups (p = 0.01). The area of the hepatic lobules in non-embolized liver was larger than in the embolized liver in all groups (p = 0.001). The ratios of the areas between non-embolized/embolized livers were 1.65, 2.19, 1.57, and 1.32 for gel, NBCA, 50-150 PVA and 700-900 PVA, respectively; the ratios of fibrosis between the embolized and non-embolized livers were 1.37, 3.01, 3.49, and 2.11 for gel, NBCA, 50-150 PVA and 700-900 PVA, respectively. Hepatic lobules in non-embolized liver were significantly larger with NBCA than in other groups (p = 0.01). Fibrosis in embolized liver was significantly higher for NBCA and 50-150 PVA (p = 0.002). The most severe changes in embolized and non-embolized liver were induced by 50-150 PVA and NCBA PVE. (orig.)
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Available from: http://dx.doi.org/10.1007/s00330-008-1277-2
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AbstractAbstract
No abstract available
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University of North West, Mmabatho (South Africa); 41 p; 1998; p. 35; National nuclear technology conference; Mmabatho (South Africa); 6-9 Sep 1998; Available from the University of North West, Private Bag X2046, Mmabatho, 2735, South Africa; Published in summary form only
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AbstractAbstract
[en] For many, looking back at 2018 might bring back memories of South Korea’s Winter Olympic Games or the British royal wedding of Prince Harry and Meghan Markle, but for pig farmers in China, the year was marked by a single event: the arrival of African swine fever (ASF). That year, the disease — once endemic to only sub-Saharan Africa — broke out among Chinese piggeries, resulting in the death or culling of over a quarter of the world’s domestic pig population. A year after its appearance, ASF was estimated to have directly cost China over a trillion yuan (US $141 billion) according to the dean of the College of Animal Science and Technology at China Agricultural University in Beijing, and caused the country’s pork prices to spike by 85 per cent.
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Also available on-line: https://www.iaea.org/bulletin/62-3
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IAEA Bulletin (Online); ISSN 1564-2690;
; v. 62(3); p. 28-29

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AbstractAbstract
[en] This article shows the method analithic, results gained from determination from crystal by struvite meet with incrustation in bars the iron, that constitute the rasper from drain by excrement and rest by food from barnyard by pigs. Too describe the transformation from this minerals to newberyte, when expose to daylight and discuss the genetic from this minerals. (author)
Original Title
Struvita: uma abordagem da sua genese
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Sociedad Uruguaya de Geologia, Montevideo (Uruguay); Facultad de Ciencias, Montevideo (Uruguay); 464 p; 1998; p. 138-141; 2. Uruguayan Geological Congress; II Congreso Uruguayo de Geologia; Montevideo (Uruguay); 13-18 May 1998; Available from: Library of The National Directorate of Mining and Geology, Montevideo, Uruguay E-mail: biblioteca@dinamige.miem.gub.uy
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AbstractAbstract
[en] For many, looking back at 2018 might bring back memories of South Korea’s Winter Olympic Games or the British royal wedding of Prince Harry and Meghan Markle, but for pig farmers in China, the year was marked by a single event: the arrival of African swine fever (ASF). That year, the disease — once endemic to only sub-Saharan Africa — broke out among Chinese piggeries, resulting in the death or culling of over a quarter of the world’s domestic pig population. A year after its appearance, ASF was estimated to have directly cost China over a trillion yuan (US $141 billion) according to the dean of the College of Animal Science and Technology at China Agricultural University in Beijing, and caused the country’s pork prices to spike by 85 per cent.
Original Title
Salvar a los cerdos de la plaga que los azota: la peste porcina africana. Protección por medio de la detección
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Also available on-line: https://www.iaea.org/es/bulletin/62-3
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IAEA Bulletin (Online); ISSN 1564-2690;
; v. 62(3); p. 28-29

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[en] Highlights: • Full-length miRNA cluster in LLT intron was deleted in PRV. • MiRNA cluster regulates PRV replication kinetics. • The intron of large latency transcript is associated with PRV virulence • MiRNA cluster defect reduced virulence in piglets. Pseudorabies virus (PRV), the etiological pathogen of Aujeszky's disease, belongs to the Alphaherpesvirus subfamily. Large latency transcript (LLT), the most abundant PRV transcript, harbors a ~ 4.6 kb microRNA (miRNA) cluster-encoding intron. To investigate the function of the LLT miRNA cluster during the life cycle of PRV, we generated a miRNA cluster mutation virus (PRV-∆miR cluster) and revertant virus. Analysis of the growth kinetics of PRV-ΔmiR cluster-infected cells revealed significantly smaller plaques and lower titers than the wild-type and revertant viruses. The mutation virus exhibited increased IE180 and decreased EP0 expression. The clinical symptoms observed in mice infected with PRV-ΔmiR cluster revealed that the miRNA cluster is involved in the pathogenesis of PRV. Physical parameters, virus shedding assays, and the SN50 titers revealed that the miRNA cluster enhances PRV virulence in pigs. Collectively, our findings suggest that the full-length miRNA cluster is involved in PRV replication and virulence.
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S0042682218301454; Available from http://dx.doi.org/10.1016/j.virol.2018.05.004; Copyright (c) 2018 Elsevier Inc.; Country of input: International Atomic Energy Agency (IAEA)
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[en] For many, looking back at 2018 might bring back memories of South Korea’s Winter Olympic Games or the British royal wedding of Prince Harry and Meghan Markle, but for pig farmers in China, the year was marked by a single event: the arrival of African swine fever (ASF). That year, the disease — once endemic to only sub-Saharan Africa — broke out among Chinese piggeries, resulting in the death or culling of over a quarter of the world’s domestic pig population. A year after its appearance, ASF was estimated to have directly cost China over a trillion yuan (US $141 billion) according to the dean of the College of Animal Science and Technology at China Agricultural University in Beijing, and caused the country’s pork prices to spike by 85 per cent.
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Also available on-line: https://www.iaea.org/ar/bulletin/62-3
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Journal Article
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IAEA Bulletin (Online); ISSN 1564-2690;
; v. 62(3); p. 28-29

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Dong, Jing; Gu, Zhenqing; Jin, Ling; Lv, Lin; Wang, Jichun; Sun, Tao; Bai, Juan; Sun, Haifeng; Wang, Xianwei; Jiang, Ping, E-mail: jiangp@njau.edu.cn2018
AbstractAbstract
[en] Highlights: • Full-genome sequencing and analysis of classical Chinese PRV strain LA. • Construction of gene-exchanging chimeric PRV strains. • Revealed the gE&gI alleles in PRV strain ZJ01 increased its virulence. An outbreak of a highly virulent pseudorabies virus strain, ZJ01, occurred in PRV-vaccinated pigs in China in 2011. In this study, ZJ01 caused fatal diseases, while the Chinese prototypic PRV strain LA caused mild respiratory disorders. Full-genome sequencing results indicate the two viruses can be classified into two sub-clusters that distinct from traditional European and US strains. To examine the potential role of the gE and gI proteins in ZJ01 virulence, we generated several recombinant viruses. In two chimeric viruses (rZJ01-LA/gEI and rLA-ZJ01/gEI), the gE and gI genes were swapped using corresponding genes from ZJ01 and LA. rZJ01-LA/gEI and the parental virus rZJ01 retained high virulence in piglets, although the survival time for rZJ01-LA/gEI infected piglets was obviously prolonged. In contrast, rLA-ZJ01/gEI exhibited higher virulence than its parental virus rLA. We conclude that changes in gE and gI proteins partly contribute to the enhanced virulence of ZJ01 strain.
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S0042682218301041; Available from http://dx.doi.org/10.1016/j.virol.2018.03.024; Copyright (c) 2018 Elsevier Inc.; Country of input: International Atomic Energy Agency (IAEA)
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[en] Highlights: • PRRSV induces HMGB1 translocation and secretion via PKCδ activation. • PKCδ knockdown in PRRSV-infected cells leads to reduction of inflammatory cytokines. • PRRSV E and pORF5a proteins are responsible for HMGB1 secretion via activating PKCδ. • E and pORF5a induce HMGB1 secretion and consequently activate inflammatory response. Porcine reproductive and respiratory syndrome virus (PRRSV) causes inflammatory injuries in infected pigs. PRRSV induces secretion of high mobility group box 1 (HMGB1) that enhances inflammatory response. However, the mechanism of PRRSV-induced HMGB1 secretion is unknown. Here, we discovered PRRSV induced HMGB1 secretion via activating protein kinase C-delta (PKCδ). HMGB1 secretion was positively correlated with PKCδ activation in PRRSV-infected cells in a dose and time-dependent manner. Suppression of PKCδ with inhibitor and siRNA significantly blocked PRRSV-induced HMGB1 translocation and secretion, which indicates PKCδ activation is essential for the PRRSV-mediated HMGB1 secretion. In addition, PKCδ knockdown in PRRSV-infected cells led to downregulation of inflammatory cytokines, including IL-1beta and IL-6. Moreover, PRRSV E and pORF5a proteins were found to activate PKCδ and consequent HMGB1 secretion. These results demonstrate PRRSV activates PKCδ to induce HMGB1 secretion via E and pORF5a. This finding provides insights on the inflammatory response and pathogenesis of PRRSV infection.
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S0042682218300631; Available from http://dx.doi.org/10.1016/j.virol.2018.02.021; Copyright (c) 2018 Elsevier Inc.; Country of input: International Atomic Energy Agency (IAEA)
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AbstractAbstract
[en] For many, looking back at 2018 might bring back memories of South Korea’s Winter Olympic Games or the British royal wedding of Prince Harry and Meghan Markle, but for pig farmers in China, the year was marked by a single event: the arrival of African swine fever (ASF). That year, the disease — once endemic to only sub-Saharan Africa — broke out among Chinese piggeries, resulting in the death or culling of over a quarter of the world’s domestic pig population. A year after its appearance, ASF was estimated to have directly cost China over a trillion yuan (US $141 billion) according to the dean of the College of Animal Science and Technology at China Agricultural University in Beijing, and caused the country’s pork prices to spike by 85 per cent.
Original Title
Stopper la peste noire porcine – Peste porcine africaine. La protection grâce à la détection
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Also available on-line: https://www.iaea.org/fr/bulletin/62-3
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Journal Article
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IAEA Bulletin (Online); ISSN 1564-2690;
; v. 62(3); p. 28-29

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