Published September 23, 2014
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Purification of radium-226 for the manufacturing of actinium-225 in a cyclotron for alpha-immunotherapy
Description
The thesis describes the development of methods for the purification of Ra-226. The objective was to obtain the radionuclide in the quality that is needed to be used as starting material in the manufacturing process for Ac-225 via proton-irradiated Ra-226. The radionuclide has been gained efficiently out of huge excesses of impurities. The high purity of the obtained radium affords its use as staring material in a pharmaceutical manufacturing process.
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Additional details
Additional titles
- Original title (German)
- Radium-Aufreinigung zur Herstellung von Actinium-225 am Zyklotron fuer die Alpha-Immuntherapie
Publishing Information
- Imprint Pagination
- 114 p.
- Report number
- INIS-DE--1939
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 46109530
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Thesis
- Descriptors DEI
- ACTINIUM 225; CYCLOTRONS; EDTA; EXTRACTION CHROMATOGRAPHY; GAMMA SPECTROSCOPY; ION EXCHANGE CHROMATOGRAPHY; ISOTOPE PRODUCTION; ISOTOPE SEPARATION; PROTON BEAMS; PROTON REACTIONS; PURIFICATION; RADIOCHEMISTRY; RADIOIMMUNOTHERAPY; RADIOPHARMACEUTICALS; RADIUM 226 TARGET
- Descriptors DEC
- ACCELERATORS; ACTINIDE NUCLEI; ACTINIUM ISOTOPES; ALPHA DECAY RADIOISOTOPES; AMINO ACIDS; BARYON REACTIONS; BEAMS; CARBOXYLIC ACIDS; CHARGED-PARTICLE REACTIONS; CHELATING AGENTS; CHEMISTRY; CHROMATOGRAPHY; CYCLIC ACCELERATORS; DAYS LIVING RADIOISOTOPES; DRUGS; HADRON REACTIONS; HEAVY NUCLEI; IMMUNOTHERAPY; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; MEDICINE; NUCLEAR MEDICINE; NUCLEAR REACTIONS; NUCLEI; NUCLEON BEAMS; NUCLEON REACTIONS; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; PARTICLE BEAMS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOLOGY; RADIOTHERAPY; SEPARATION PROCESSES; SPECTROSCOPY; TARGETS; THERAPY