[en] ¹⁶⁹Yb was produced by thermal neutron irradiation of Yb₂O₃ in 1 MW research reactor at Cekmece Nuclear Research Center. ¹⁶⁹Yb-EDTA complex was then prepared with a sodium salt of EDTA. Radionuclidic and radiochemical purities of the compound were determined by gama spectral analysis and radiochromatography-electrophoresis following preparation. Ionic Yb(III) which accumulates at bone and liver was not observed on the radiochromatographic and electrophoretic analysis of the final compound. There was no separation of the label for two months of examination in order to determine stability of the compound. In conclusion, the labeled compound has been prepared for use in the external scanning of kidney and determining the glomerular filtration rate. The label appears to be firmly bound so that the agent can be stored for a reasonably long period as 31 days half-life of ¹⁶⁹Yb permits. Administration of the compound is safe from the stand point of radiation dose since a 30 micro-Ci ¹⁶⁹Yb-EDTA for a glomerular filtration study delivers no more than 0.4 mrad whole-body and 5 mrad kidney dose. (author)