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Shipler, D.B.; Ballou, J.E.; Griffin, B.I.; Nelson, I.C.
Diagnosis and treatment of incorporated radionuclides1976
Diagnosis and treatment of incorporated radionuclides1976
AbstractAbstract
[en] Rats and beagles were exposed by inhalation to an aerosol containing stable Sm2O3 tagged with 145Sm2O3 and 143Pm2O3. The animals were sacrificed at 0, 14 and 30 days post-exposure to compare the kinetics and translocation of 145Sm and 143Pm. Quantitative analysis for 145Sm and 143Pm in several tissues and excreta indicate that the two rare-earth elements were mobilized and distributed similarly by the rats and dogs. Results indicate that within the error of the measurement technique, samarium acts as a carrier for promethium. The data also indicate that activities measured in faecal samples could be used to predict lung burdens of 147Pm. At activity levels and sintering temperatures employed in the rat exposures, there was sufficient activity in urine samples to permit its use as an indicator of lung burdens of 147Pm. At activity levels and sintering temperatures employed in the dog exposures, this was not the case. (author)
Original Title
Sm 145, Pm 143 kinetics
Primary Subject
Source
International Atomic Energy Agency, Vienna (Austria); World Health Organization, Geneva (Switzerland); Proceedings series; p. 209-221; ISBN 92-0-020176-8;
; 1976; p. 209-221; IAEA; Vienna; International seminar on diagnosis and treatment of incorporated radionuclides; Vienna, Austria; 8 - 12 Dec 1975; IAEA-SR--6/28

Record Type
Book
Literature Type
Conference
Country of publication
ANIMALS, BETA DECAY RADIOISOTOPES, BIOLOGICAL MATERIALS, BIOLOGICAL WASTES, BODY, BODY FLUIDS, CHALCOGENIDES, COLLOIDS, DAYS LIVING RADIOISOTOPES, DISPERSIONS, DOGS, ELECTRON CAPTURE RADIOISOTOPES, EVEN-ODD NUCLEI, INTAKE, INTERMEDIATE MASS NUCLEI, ISOTOPES, KINETICS, MAMMALS, NUCLEI, ODD-EVEN NUCLEI, ORGANS, OXIDES, OXYGEN COMPOUNDS, PROMETHIUM COMPOUNDS, PROMETHIUM ISOTOPES, RADIOISOTOPES, RARE EARTH COMPOUNDS, RARE EARTH NUCLEI, RESPIRATORY SYSTEM, RODENTS, SAMARIUM COMPOUNDS, SAMARIUM ISOTOPES, SOLS, VERTEBRATES, WASTES
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