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AbstractAbstract
[en] Neovascularization was induced surgically in normally avascular canine corneas to study the radioresponse of slowly proliferating capillary endothelial cells. Neovascularization was stimulated for 7 days. Corneal tissue samples were evaluated quantitatively by morphometric methods. Dose-response curves were drawn by plotting percent capillary volumes versus dose. Irradiation was given with either 60Co γ rays or 168 MeV/c negative π mesons. The dose rate for π mesons was about 30 rad/min. The D0 was 265 rad for γ rays and 155 rad for pions. The ratio of D0 values gave a relative biologic effectiveness (RBE) of 1.7. Using 60Co as a standard, an RBE of 1.6 was calculated at the 1% capillary volume level
Original Title
Comparison of effects on proliferation of capillary epithelial cells in canine corneas
Primary Subject
Record Type
Journal Article
Journal
Int. J. Radiat. Oncol., Biol. Phys; v. 4(9/10); p. 825-828
Country of publication
ANIMALS, ANTIMATTER, ANTIMESONS, ANTIPARTICLES, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BIOLOGICAL EFFECTS, BLOOD VESSELS, BODY, BOSONS, CARDIOVASCULAR SYSTEM, COBALT ISOTOPES, ELECTROMAGNETIC RADIATION, ELEMENTARY PARTICLES, EYES, HADRONS, INTERMEDIATE MASS NUCLEI, IONIZING RADIATIONS, IRRADIATION, ISOMERIC TRANSITION ISOTOPES, ISOTOPES, MAMMALS, MATTER, MESONS, MINUTES LIVING RADIOISOTOPES, NUCLEI, ODD-ODD NUCLEI, ORGANS, PIONS, PSEUDOSCALAR ANTIMESONS, PSEUDOSCALAR MESONS, RADIATION EFFECTS, RADIATIONS, RADIOISOTOPES, SENSE ORGANS, VERTEBRATES, YEARS LIVING RADIOISOTOPES
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