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AbstractAbstract
[en] According to the invention a radioimmunoassay has been developed for the in-vitro determination of thyroxine in non-extracted blood serum. The radioactive thyroxine is labelled with iodine 125 or iodine 131. The corresponding antiserum contains special thyroxine antibodies. The immunogen to produce the antiserum contains a conjugate of the N-acetyl derivative of thyroxine compled to bovin serum albumin with 1-ethyl-3-(3-dimethyl-amino-propyl)-carbodiimide. (VJ)
[de]
Erfindungsgemaess wurde ein Radioimmuntest zur in-vitro-Bestimmung von Thyroxin in nicht-extrahiertem Blutserum entwickelt. Das radioaktive Thyroxin wird mit Jod-125 bzw. Jod-131 markiert. Das entsprechende Antiserum enthaelt spezielle Thyroxin-Antikoerper. Das Immunogen zur Herstellung des Antiserums enthaelt ein Konjugat des N-Acetylderivats von Thyroxin gekoppelt an Rinderserumalbumin mit 1-Aethyl-3-(3-dimethylaminopropyl)-carbodiimid. (VJ)Original Title
Verfahren zur radioimmunologischen in-vitro-Bestimmung von Thyroxin und abgepacktes Testbesteck zur Durchfuehrung dieses Verfahrens
Primary Subject
Source
13 Jan 1977; 36 p; DE PATENT DOCUMENT 2627455/A/
Record Type
Patent
Country of publication
AMINO ACIDS, BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, CARBOXYLIC ACIDS, DAYS LIVING RADIOISOTOPES, ELECTRON CAPTURE RADIOISOTOPES, HORMONES, INTERMEDIATE MASS NUCLEI, IODINE ISOTOPES, ISOTOPE APPLICATIONS, ISOTOPES, NUCLEI, ODD-EVEN NUCLEI, ORGANIC ACIDS, ORGANIC COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANIC IODINE COMPOUNDS, PEPTIDE HORMONES, PROTEINS, RADIOISOTOPES, THYROID HORMONES, TRACER TECHNIQUES
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