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AbstractAbstract
[en] The visualization of functioning adrenocortical tissue by scintigraphy became possible with the introduction of radioiodinated cholesterol derivatives. According to the literature, there is evidence that one of these iodinated cholesterols, 6-β-iodomethyl-nor-cholesterol, concentrates in the adrenal cortex to a much greater extent than 131I-19-odocholesterol. Results comparing both radiopharmaceuticals are described. The authors investigated the possibility of increasing the uptake of iodinated cholesterol using simultaneous ACTH and the 'cholesterol side-chain cleavage enzymeblocker': aminoglutethimide. The results of adrenal scintigraphy performed in 37 patients are described. Finally, the literature on adrenal scintigraphy is reviewed, and results reported in various studies are compared. (Auth.)
Primary Subject
Source
13 Jun 1978; 108 p; Proefshrift (Dr.).
Record Type
Miscellaneous
Literature Type
Thesis/Dissertation
Report Number
Country of publication
BETA DECAY RADIOISOTOPES, BETA-MINUS DECAY RADIOISOTOPES, BODY, COUNTING TECHNIQUES, DAYS LIVING RADIOISOTOPES, DIAGNOSTIC TECHNIQUES, DISEASES, DRUGS, ENDOCRINE DISEASES, ENDOCRINE GLANDS, GLANDS, HYDROXY COMPOUNDS, INTERMEDIATE MASS NUCLEI, IODINE ISOTOPES, ISOTOPES, LABELLED COMPOUNDS, MEDICINE, NEOPLASMS, NUCLEAR MEDICINE, NUCLEI, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANS, RADIOACTIVE MATERIALS, RADIOISOTOPE SCANNING, RADIOISOTOPES, STEROIDS
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