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AbstractAbstract
[en] Several cell kinetic parameters of the mammary adenocarcinoma EO 771 were evaluated by means of tumor volume measurements and of 125I-UdR. The in-situ measured activity loss rate is disturbed by a slow elimination of labelled necrotic cells and by reutilization of 125I-UdR. The restrictions of the I-UdR method are mentioned and the measured activity loss rates are compared with calculated volume loss rates. (orig./MG)
[de]
Mehrere zellkinetische Parameter des Adenokarzinoms der Brust EO 771 wurden mit Hilfe der Tumorvolumenmessung und der 125I-UdR-Methode untersucht. Die in-situ gemessene Aktivitaetsverlustrate wird aufgrund einer langsamen Eliminierung nekrotischer Zellen und der Wiederaufnahme von 125I-UdR verzerrt. Die Grenzen der I-UdR-Methode werden dargestellt, die gemessenen Aktivitaetsverlustraten mit berechneten Volumenverlustraten verglichen. (orig./MG)Primary Subject
Source
1978; 11 p; 14. annual meeting of the European Society of Radiation Biology; Juelich, Germany, F.R; 9 - 13 Oct 1978
Record Type
Miscellaneous
Literature Type
Conference
Report Number
Country of publication
ANIMAL CELLS, ANIMALS, ANTIMETABOLITES, ANTIMITOTIC DRUGS, AZINES, BETA DECAY RADIOISOTOPES, DAYS LIVING RADIOISOTOPES, DISEASES, DRUGS, ELECTRON CAPTURE RADIOISOTOPES, HETEROCYCLIC COMPOUNDS, HYDROXY COMPOUNDS, INJECTION, INTAKE, INTERMEDIATE MASS NUCLEI, IODINE ISOTOPES, IODOURACILS, ISOTOPE APPLICATIONS, ISOTOPES, MAMMALS, NEOPLASMS, NUCLEI, NUCLEOSIDES, NUCLEOTIDES, ODD-EVEN NUCLEI, ORGANIC COMPOUNDS, ORGANIC HALOGEN COMPOUNDS, ORGANIC IODINE COMPOUNDS, ORGANIC NITROGEN COMPOUNDS, PYRIMIDINES, RADIOISOTOPES, RIBOSIDES, RODENTS, URACILS, VERTEBRATES
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