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Sutton, W.W.; Patzer, R.G.; Hahn, P.B.; Potter, G.D.
Environmental Protection Agency, Las Vegas, NV (USA). Environmental Monitoring and Support Lab1979
Environmental Protection Agency, Las Vegas, NV (USA). Environmental Monitoring and Support Lab1979
AbstractAbstract
[en] Lactating cows and goats were used to examine the biological transport of curium-243 in dairy animals. After either single oral or intravenous nuclide doses were administered, samples of milk, urine, blood, and feces were taken over a 144-hr priod, and the curium concentrations were determined by gamma counting. Gastrointestinal uptake of curium was estimated to be 0.02 and 0.006% of the oral dose for cows and goats, respectively. The cumulative percentage of oral dose transported to milk and urine was 4.6 x 10-4 and 1.9 x 10-3, respectively, for a cow and 2.7 x 10-4 and 1.6 x 10-4, respectively, for goats. Plasma concentrations of curium decreased rapidly following all intravenous injections. The average percentage of injected curium transferred to milk, urine, and feces was 2, 8, and 1, respectively, for a cow and 2, 5, and 5, respectively, for goats. All animals were sacrificed one week after dosing. Bovine bone retained the greatest fraction of the administered dose and the next highest was the liver. However, in all three intravenously dosed goats the liver contained the greatest amount of curium. Nuclide deposition in bone and liver was essentially equal for two of the three orally dosed goats while the skeleton contained the most curium in the other animal. Comparisons are presented between curium-243 and americium-241 transport in dairy cows
Original Title
Comparison to 241Am kinetics in lactating cows and goats
Primary Subject
Source
Apr 1979; 27 p; Available from NTIS., PC A03/MF A01
Record Type
Report
Literature Type
Numerical Data
Report Number
Country of publication
AMERICIUM 241, BLOOD PLASMA, BLOOD-PLASMA CLEARANCE, COMPARATIVE EVALUATIONS, COWS, CURIUM 243, DISTRIBUTION, EXPERIMENTAL DATA, FECES, GOATS, INTESTINAL ABSORPTION, INTRAVENOUS INJECTION, ISOLATED VALUES, LACTATION, LIVER, MILK, ORAL ADMINISTRATION, RADIOACTIVITY, RADIONUCLIDE KINETICS, SINGLE INTAKE, SKELETON, TISSUES, URINE
ACTINIDE NUCLEI, ALPHA DECAY RADIOISOTOPES, AMERICIUM ISOTOPES, ANIMALS, BIOLOGICAL MATERIALS, BIOLOGICAL WASTES, BLOOD, BODY, BODY FLUIDS, CATTLE, CLEARANCE, CURIUM ISOTOPES, DATA, DATA FORMS, DIGESTIVE SYSTEM, DOMESTIC ANIMALS, EVEN-ODD NUCLEI, FOOD, GLANDS, HEAVY NUCLEI, INFORMATION, INJECTION, INTAKE, ISOTOPES, KINETICS, MAMMALS, NUCLEI, NUMERICAL DATA, ODD-EVEN NUCLEI, ORGANS, RADIOISOTOPES, RUMINANTS, UPTAKE, VERTEBRATES, WASTES, YEARS LIVING RADIOISOTOPES
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